Evidence map›Paper›PMID 30310276›Full record

ArticleInternational journal of nanomedicine2018

Determination of dose enhancement caused by AuNPs with Xoft

Elham Shahhoseini, Prabhakar Ramachandran, William Roy Patterson, Moshi Geso

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Elham ShahhoseiniDiscipline of Medical Radiation, School of Health and Biomedical Sciences, RMIT University, Bundoora, VIC, Australia, moshi.geso@rmit.edu.au.
Prabhakar RamachandranDiscipline of Medical Radiation, School of Health and Biomedical Sciences, RMIT University, Bundoora, VIC, Australia, moshi.geso@rmit.edu.au.
William Roy PattersonAndrew Love Cancer Centre, Geelong Hospital, Geelong, VIC, Australia.
Moshi GesoDiscipline of Medical Radiation, School of Health and Biomedical Sciences, RMIT University, Bundoora, VIC, Australia, moshi.geso@rmit.edu.au.
Active Medicine (United Kingdom) · GBGeelong Hospital · AUPeter MacCallum Cancer Centre · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to determine dose enhancement (DE) and the possible clinical benefits associated with the inclusion of gold nanoparticles (AuNPs) in cancer cells irradiated by either an PATIENTS AND

methodsBrachytherapy DE caused by AuNPs is investigated using two methods, namely

resultsHigh dose enhancement factor (DEF) values were achieved in treated groups with low concentration of AuNPs with the 50 kV energy associated with the eBx™. The DE levels in eBx™ for Du145 and A549 cells were found to be 2.90 and 2.06, respectively. The results showed DEFs measured for the same cell lines using

conclusionThe higher DE values obtained with eBx™ compared to

Indexed as

BrachytherapyA549 CellsCell DeathCell SurvivalDose-Response Relationship, RadiationGoldHumansIridium RadioisotopesLinear ModelsMetal NanoparticlesRadiation ToleranceRadiotherapy DosageX-RaysGoldIridium-192Iridium Radioisotopes192Ir brachytherapydose enhancement factorgold nanoparticleslung cancer cellsprostate cancer cellsXoft® Axxent® Electronic Brachytherapy (eBx™)

Identifiers

PMID30310276
PMCPMC6165788
OpenAlexW2890579853

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.