Evidence map›Paper›PMID 30310271›Full record

ArticleInternational journal of chronic obstructive pulmonary disease

The impact of 2011 and 2017 Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) guidelines on allocation and pharmacological management of patients with COPD in Taiwan: Taiwan Obstructive Lung Disease (TOLD) study.

Meng-Jer Hsieh, Shu-Yi Huang, Tsung-Ming Yang, Chi-Wei Tao, Shih-Lung Cheng, Chao-Hsien Lee, Ping-Hung Kuo, Yao-Kuang Wu, Ning-Hung Chen, Wu-Huei Hsu and 5 more

Abstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Correlation between TNF-BioMed research international · 2021
    Trial
  3. Trial
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Total Sleep Time in the Taiwan Obstructive Lung Disease Cohort.International journal of environmental research and public health · 2021
    Observational
  15. Does Evaluation and Management of COPD Follow Therapeutic Strategy Recommendations?Chronic obstructive pulmonary diseases (Miami, Fla.) · 2021
    Article
  16. Article
  17. Observational
  18. Article
  19. Effectiveness of Nationwide COPD Pay-for-Performance Program on COPD Exacerbations in Taiwan.International journal of chronic obstructive pulmonary disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Meng-Jer HsiehDepartment of Pulmonary and Critical Care Medicine, Chiayi Chang Gung Memorial Hospital, Chang-Gung Medical foundation, Chiayi, Taiwan, chestmed@cgmh.org.tw.
Shu-Yi HuangDepartment of Pulmonary and Critical Care Medicine, Chiayi Chang Gung Memorial Hospital, Chang-Gung Medical foundation, Chiayi, Taiwan, chestmed@cgmh.org.tw.
Tsung-Ming YangDepartment of Pulmonary and Critical Care Medicine, Chiayi Chang Gung Memorial Hospital, Chang-Gung Medical foundation, Chiayi, Taiwan, chestmed@cgmh.org.tw.
Chi-Wei TaoDepartment of Internal Medicine, Cheng Hsin General Hospital, Taipei, Taiwan.
Shih-Lung ChengDepartment of Internal Medicine, Far Eastern Memorial Hospital, Taipei.
Chao-Hsien LeeDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, Taiwan.
Ping-Hung KuoDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Yao-Kuang WuDivision of Pulmonary Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan.
Ning-Hung ChenDepartment of pulmonary and critical care medicine, LinKou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Wu-Huei HsuDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.
Jeng-Yuan HsuDivision of Chest Medicine, Taichung Veterans General Hospital, Taiwan.
Ming-Shian LinDpartment of Internal Medicine, Ditmanson Medical Foundation, Chia-Yi Cristian Hospital, Chia-Yi, Taiwan.
Chin-Chou WangDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang-Gung Medical Foundation, Kaohsiung, Taiwan.
Yu-Feng WeiDepartment of Internal Medicine E-Da Hospital, I-Shou University, Kaohsiung, Taiwan.
Ying-Huang TsaiDepartment of Pulmonary and Critical Care Medicine, Chiayi Chang Gung Memorial Hospital, Chang-Gung Medical foundation, Chiayi, Taiwan, chestmed@cgmh.org.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis nationwide study was performed to evaluate the evolution of distributions of patients with COPD according to the 2011 and 2017 Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) guidelines and to assess the concordance between the prescribed medications and the pharmacological management recommended by the two distinct classification systems in Taiwan. SUBJECTS AND

methodsData were retrospectively retrieved from stable COPD patients in 11 participating hospitals across Taiwan. Patients were grouped according to GOLD 2011 and 2017 guidelines respectively. Definitions of undertreatment and overtreatment were based on the pharmacological recommendations in the individual guidelines.

resultsA total of 1,053 COPD patients were included. The percentages of patients in GOLD 2011 groups A, B, C and D were 18.4%, 40.6%, 6.7% and 34.2%, respectively. When reclassified according to the GOLD 2017, the percentages of group A and B increased to 23.3% and 63.2%, and groups C and D decreased to 1.9% and 11.6%, respectively. Up to 67% of patients in GOLD 2011 groups C and D were reclassified to GOLD 2017 groups A and B. The pharmacological concordance rate was 60.9% for GOLD 2011 and decreased to 44.9% for GOLD 2017. Overtreatment was found in 29.5% of patients according to GOLD 2011 and the rate increased to 46.1% when classified by the GOLD 2017. The major cause of overtreatment was unnecessary inhaled corticosteroids and the main cause of undertreatment was a lack of maintenance long-acting bronchodilators.

conclusionThe distribution of COPD patients in Taiwan was more uneven with the GOLD 2017 than with the GOLD 2011. A pharmacological discordance to the guidelines was identified. Updated guidelines with reclassification of COPD patients resulted in more discordance between prescribed medications and the guidelines. Physicians should make proper adjustments of the prescriptions according to the updated guidelines to ensure the mostly appropriate treatment for COPD patients.

Indexed as

Practice Guidelines as TopicAdministration, InhalationAdrenal Cortex HormonesAgedBronchodilator AgentsFemaleGlobal HealthGuideline AdherenceHumansMaleMiddle AgedOutcome Assessment, Health CarePulmonary Disease, Chronic ObstructiveRetrospective StudiesSeverity of Illness IndexTaiwanAdrenal Cortex HormonesBronchodilator Agentschronic obstructive pulmonary diseaseGOLD guidelinesinhaled corticosteroidslong-acting bronchodilators

Identifiers

PMID30310271
PMCPMC6165725

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.