Evidence map›Paper›PMID 30310268›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2018

Characteristics of diabetic macular edema on optical coherence tomography may change over time or after treatment.

Shwu-Jiuan Sheu, Ying-Yen Lee, Yu-Harn Horng, Huey-Shyan Lin, Wei-Yu Lai, Chui-Lien Tsen

Abstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Intraocular pressure might play a role in the surgical management of patients with epiretinal membrane.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shwu-Jiuan SheuDepartment of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, sjiuansheu@gmail.com.
Ying-Yen LeeDepartment of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, sjiuansheu@gmail.com.
Yu-Harn HorngDepartment of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, sjiuansheu@gmail.com.
Huey-Shyan LinDepartment of Health-Business Administration, Fooyin University, Kaohsiung, Taiwan.
Wei-Yu LaiDepartment of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, sjiuansheu@gmail.com.
Chui-Lien TsenDepartment of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, sjiuansheu@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate optical coherence tomography (OCT) characteristics in diabetic macular edema (DME) over time and after treatment. PATIENTS AND

methodsOCT morphological features in DME eyes treated with ranibizumab with at least 1 year of follow-up were retrospectively analyzed.

resultsThirty-five eyes were included. From baseline to Month 12, mean visual gain was 7.2±13.6 letters and mean central retinal thickness reduction was 61.9±121.8 μm. Fovea-involving ellipsoid zone (EZ) disruption was significantly associated with final vision of <70 letters. Subretinal fluid at baseline was present only in eyes naïve to previous intravitreal pharmacotherapy and was related to better visual gain and fewer injections. Treatment-naïve eyes had shorter DME duration and less EZ damage.

conclusionDME characteristics on OCT may change over time or after treatment. Subretinal fluid may be associated with earlier change and less EZ damage in DME.

Indexed as

diabetic macular edemaOCToptical coherence tomographySRFsubretinal fluidvascular endothelial growth factorVEGF

Identifiers

PMID30310268
PMCPMC6165769

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.