Evidence map›Paper›PMID 30310164›Full record

ArticleScientific reports2018

Multi-compartment scaffold fabricated via 3D-printing as in vitro co-culture osteogenic model.

Elvira De Giglio, Maria A Bonifacio, Ana M Ferreira, Stefania Cometa, Zhi Yuan Ti, Antonella Stanzione, Kenny Dalgarno, Piergiorgio Gentile

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Elvira De GiglioDepartment of Chemistry, University of Bari Aldo Moro, Via E. Orabona 4, Bari, 70126, Italy. elvira.degiglio@uniba.it.
Maria A BonifacioDepartment of Chemistry, University of Bari Aldo Moro, Via E. Orabona 4, Bari, 70126, Italy.
Ana M FerreiraSchool of Engineering, Newcastle University, Stephenson Building, Claremont Road, Newcastle upon Tyne, NE1 7RU, UK.ORCID http://orcid.org/0000-0002-7728-1619
Stefania CometaJaber Innovation s.r.l., via Calcutta 8, Rome, 00144, Italy.
Zhi Yuan TiSchool of Engineering, Newcastle University, Stephenson Building, Claremont Road, Newcastle upon Tyne, NE1 7RU, UK.
Antonella StanzioneDepartment of Chemistry, University of Bari Aldo Moro, Via E. Orabona 4, Bari, 70126, Italy.
Kenny DalgarnoSchool of Engineering, Newcastle University, Stephenson Building, Claremont Road, Newcastle upon Tyne, NE1 7RU, UK.
Piergiorgio GentileSchool of Engineering, Newcastle University, Stephenson Building, Claremont Road, Newcastle upon Tyne, NE1 7RU, UK. piergiorgio.gentile@ncl.ac.uk.ORCID http://orcid.org/0000-0002-3036-6594
Newcastle University · GBUniversity of Bari Aldo Moro · IT

Funding

ACTIVE SPECIFIC IMMUNOTHERAPY IN MAN: A MURINE MODELR01CA029592 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KAHAN, BARRY D · 1985 to 1987
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ACTIVE SPECIFIC IMMUNOTHERAPY IN MAN: A MURINE MODELR37CA029592 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KAHAN, BARRY D · 1988 to 1992
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Engineering and Physical Sciences Research Council (EPSRC) EP/K029592/1
6 · The paper itself

Abstract

The development of in vitro 3D models to get insights into the mechanisms of bone regeneration could accelerate the translation of experimental findings to the clinic, reducing costs and duration of experiments. This work explores the design and manufacturing of multi-compartments structures in poly(ε-caprolactone) (PCL) 3D-printed by Fused Filament Fabrication technique. The construct was designed with interconnected stalls to host stem cells and endothelial cells. Cells were encapsulated within an optimised gellan gum (GG)-based hydrogel matrix, crosslinked using strontium (Sr

Indexed as

OsteogenesisPrinting, Three-DimensionalCalciumCell LineCoculture TechniquesCompressive StrengthHumansHuman Umbilical Vein Endothelial CellsHydrogelsMesenchymal Stem CellsOsteoblastsPolyestersPolysaccharides, BacterialStrontiumTissue EngineeringTissue ScaffoldsCalciumgellan gumHydrogelspolycaprolactonePolyestersPolysaccharides, BacterialStrontium

Identifiers

PMID30310164
PMCPMC6181937
OpenAlexW2895468489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.