Evidence map›Paper›PMID 30310114›Full record

ArticleScientific reports2018

Insight into the draft whole-genome sequence of the dermatophyte Arthroderma vanbreuseghemii.

Mohamed Mahdi Alshahni, Tsuyoshi Yamada, Ayaka Yo, Somay Y Murayama, Makoto Kuroda, Yasutaka Hoshino, Jun Ishikawa, Shinichi Watanabe, Koichi Makimura

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trichophyton indotineae: Epidemiology, antifungal resistance and antifungal stewardship strategies.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Review
  3. Article
  4. Gene Amplification ofAntimicrobial agents and chemotherapy · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mohamed Mahdi AlshahniInstitute of Medical Mycology, Teikyo University, 2-11-1, Kaga, Itabashi, Tokyo, 173-8605, Japan.
Tsuyoshi YamadaTeikyo University Institute of Medical Mycology, 359 Otsuka, Hachioji, Tokyo, 192-0395, Japan.
Ayaka YoInstitute of Medical Mycology, Teikyo University, 2-11-1, Kaga, Itabashi, Tokyo, 173-8605, Japan.
Somay Y MurayamaLaboratory of Medical Microbiology, School of Pharamcy, Nihon University, Narashinodai 7-7-1, Funabashi, Chiba, 274-8555, Japan.
Makoto KurodaPathogen Genomics Center, National Institute of Infectious Diseases, Toyama 1-23-1, Shinjuku, Tokyo, 162-8640, Japan.
Yasutaka HoshinoDepartment of Bioactive Molecules, National Institute of Infectious Diseases, Toyama 1-23-1, Shinjuku, Tokyo, 162-8640, Japan.
Jun IshikawaDepartment of Bioactive Molecules, National Institute of Infectious Diseases, Toyama 1-23-1, Shinjuku, Tokyo, 162-8640, Japan.
Shinichi WatanabeTeikyo University Institute of Medical Mycology, 359 Otsuka, Hachioji, Tokyo, 192-0395, Japan.
Koichi MakimuraInstitute of Medical Mycology, Teikyo University, 2-11-1, Kaga, Itabashi, Tokyo, 173-8605, Japan. makimura@med.teikyo-u.ac.jp.
Teikyo University · JPNational Institute of Infectious Diseases · JPNihon University · JPOtsuka (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Next-generation technologies have prompted efforts towards generating a large repertoire of whole-genome sequences. The dermatophyte Arthroderma vanbreuseghemii has been considered as a good model in which to conduct molecular biological studies on this fungal group. Despite the considerable repertoire of molecular tools developed for this fungus, the lack of genomic data has represented a major limitation, preventing effective implementation of those tools. Herein, the authors report the first draft whole-genome sequence of this dermatophytic species. The size of the draft genome was 23 Mb, exhibiting a GC content of 48.1%. Given the significance of secreted proteases in tissue invasion, a comparative analysis of genes encoding extracellular proteases was performed between A. vanbreuseghemii and other dermatophytes. Furthermore, genes that might be involved in DNA repair also were compared among dermatophytes. Moreover, the complete mitochondrial genome of A. vanbreuseghemii was obtained and shown to consist of 24,287 bp with a GC content of 24%. In conclusion, the availability of genomic data for A. vanbreuseghemii is expected to facilitate the implementation of the molecular tools established for this fungus, enhancing our understanding of the biology of dermatophytes.

Indexed as

Genome, FungalGenomicsArthrodermataceaeBase CompositionDNA RepairEvolution, MolecularGenome SizePhylogenySequence Analysis, DNAWhole Genome Sequencing

Identifiers

PMID30310114
PMCPMC6181936
OpenAlexW2895521030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.