Evidence map›Paper›PMID 30310069›Full record

ReviewNature reviews. Disease primers2018

Immune-mediated neuropathies.

Bernd C Kieseier, Emily K Mathey, Claudia Sommer, Hans-Peter Hartung

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Disease primers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 3 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 3 syntheses or guidelines pooled it, 138 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Review
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  13. Antibody glycosylation in neuroimmune diseases.Journal of translational medicine · 2025
    Review
  14. Article
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  17. Article
  18. Article
  19. Diabetic neuropathy: cutting-edge research and future directions.Signal transduction and targeted therapy · 2025
    Review
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Bernd C KieseierDepartment of Neurology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany. bernd.kieseier@uni-duesseldorf.de.
Emily K MatheyNeuroinflammation Laboratory, Brain and Mind Centre, University of Sydney, Sydney, Australia.
Claudia SommerDepartment of Neurology, University of Würzburg, Würzburg, Germany.
Hans-Peter HartungDepartment of Neurology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Heinrich Heine University Düsseldorf · DEUniversity of Sydney · AUUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the discovery of an acute monophasic paralysis, later coined Guillain-Barré syndrome, almost 100 years ago, and the discovery of chronic, steroid-responsive polyneuropathy 50 years ago, the spectrum of immune-mediated polyneuropathies has broadened, with various subtypes continuing to be identified, including chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and multifocal motor neuropathy (MMN). In general, these disorders are speculated to be caused by autoimmunity to proteins located at the node of Ranvier or components of myelin of peripheral nerves, although disease-associated autoantibodies have not been identified for all disorders. Owing to the numerous subtypes of the immune-mediated neuropathies, making the right diagnosis in daily clinical practice is complicated. Moreover, treating these disorders, particularly their chronic variants, such as CIDP and MMN, poses a challenge. In general, management of these disorders includes immunotherapies, such as corticosteroids, intravenous immunoglobulin or plasma exchange. Improvements in clinical criteria and the emergence of more disease-specific immunotherapies should broaden the therapeutic options for these disabling diseases.

Indexed as

Adrenal Cortex HormonesAntibodies, MonoclonalDiagnosis, DifferentialGuillain-Barre SyndromeHumansImmunoglobulins, IntravenousPlasmapheresisPolyradiculoneuropathy, Chronic Inflammatory DemyelinatingAdrenal Cortex HormonesAntibodies, MonoclonalImmunoglobulins, Intravenous

Identifiers

PMID30310069
OpenAlexW2897749707

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.