Evidence map›Paper›PMID 30309992›Full record

ArticleBMJ open2018

Detection and treatment initiation for depression and alcohol use disorders: facility-based cross-sectional studies in five low-income and middle-income country districts.

Sujit D Rathod, Tessa Roberts, Girmay Medhin, Vaibhav Murhar, Sandesh Samudre, Nagendra P Luitel, One Selohilwe, Joshua Ssebunnya, Mark J D Jordans, Arvin Bhana and 6 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 69 citations in OpenAlex.

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  13. Alcohol use disorder research in India: An update.Indian journal of psychiatry · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 7 countries.

Sujit D RathodDepartment of Population Health, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0001-8783-7724
Tessa RobertsCentre for Global Mental Health, Department of Population Health, London School of Hygiene and Tropical Medicine, London, UK.
Girmay MedhinAklilu Lemma Institute of Pathology, Addis Ababa University, Addis Ababa, Ethiopia.
Vaibhav MurharSangath, Bhopal, Madhya Pradesh, India.
Sandesh SamudreDepartment of Health Services and Population Research, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Nagendra P LuitelTranscultural Psychosocial Organization (TPO), Kathmandu, Nepal.
One SelohilweCentre for Rural Health, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
Joshua SsebunnyaMakerere University/Butabika National Referral and Teaching Mental Hospital, Kampala, Uganda.
Mark J D JordansCentre for Global Mental Health, Institute of Psychiatry, Psychology and Neurosciences, King's College London, London, UK.
Arvin BhanaCentre for Rural Health, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.ORCID 0000-0003-4235-0108
Inge PetersenCentre for Rural Health, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
Fred KigoziMakerere University/Butabika National Referral and Teaching Mental Hospital, Kampala, Uganda.
Juliet NakkuMakerere University/Butabika National Referral and Teaching Mental Hospital, Kampala, Uganda.
Crick LundCentre for Global Mental Health, Institute of Psychiatry, Psychology and Neurosciences, King's College London, London, UK.
Abebaw Fekadu *Centre for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Rahul Shidhaye *Centre for Mental Health, Public health foundation of India, New Delhi, India.
Butabika Hospital · UGKing's College London · GBUniversity of KwaZulu-Natal · ZAAddis Ababa University · ETBrighton and Sussex Medical School · GBLondon School of Hygiene & Tropical Medicine · GBMaastricht University · NLNLR Nepal · NPSangath · INSouth African Medical Research Council · ZAUniversity of Cape Town · ZA

Funding

Medical Research Council MR/M025470/1
6 · The paper itself

Abstract

objectivesTo estimate the proportion of adult primary care outpatients who are clinically detected and initiate treatment for depression and alcohol use disorder (AUD) in low-income and middle-income country (LMIC) settings.

designFive cross-sectional studies.

settingAdult outpatient services in 36 primary healthcare facilities in Sodo District, Ethiopia (9 facilities); Sehore District, India (3); Chitwan District, Nepal (8); Dr Kenneth Kaunda District, South Africa (3); and Kamuli District, Uganda (13).

participantsBetween 760 and 1893 adults were screened in each district. Across five districts, between 4.2% and 20.1% screened positive for depression and between 1.2% and 16.4% screened positive for AUD. 96% of screen-positive participants provided details about their clinical consultations that day. PRIMARY OUTCOMES: Detection of depression, treatment initiation for depression, detection of AUD and treatment initiation for AUD.

resultsAmong depression screen-positive participants, clinical detection of depression ranged from 0% in India to 11.7% in Nepal. Small proportions of screen-positive participants received treatment (0% in Ethiopia, India and South Africa to 4.2% in Uganda). Among AUD screen-positive participants, clinical detection of AUD ranged from 0% in Ethiopia and India to 7.8% in Nepal. Treatment was 0% in all countries aside Nepal, where it was 2.2%.

conclusionsThe findings of this study suggest large detection and treatment gaps for adult primary care patients, which are likely contributors to the population-level mental health treatment gap in LMIC. Primary care facilities remain unfulfilled intervention points for reducing the population-level burden of disease in LMIC.

Indexed as

AdultAlcoholismCross-Sectional StudiesDepressive DisorderDeveloping CountriesFemaleHumansMaleMiddle AgedPovertyYoung Adultalcohol use disorderclinical detectionlow- and middle-income countriesprimary care

Identifiers

PMID30309992
PMCPMC6252626
OpenAlexW2896543174

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.