Evidence map›Paper›PMID 30309982›Full record

ArticleThe Journal of biological chemistry2018

The matrix domain of the Gag protein from avian sarcoma virus contains a PI(4,5)P

Susan M Watanabe, Gisselle N Medina, Gunnar N Eastep, Ruba H Ghanam, Jiri Vlach, Jamil S Saad, Carol A Carter

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Susan M WatanabeFrom the Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York 11794 and.
Gisselle N MedinaFrom the Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York 11794 and.
Gunnar N Eastepthe Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama 35294.
Ruba H Ghanamthe Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama 35294.
Jiri Vlachthe Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama 35294.
Jamil S Saadthe Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama 35294.ORCID 0000-0001-9503-6484
Carol A CarterFrom the Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York 11794 and carol.carter@stonybrook.edu.
University of Alabama at Birmingham · USStony Brook University · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Omer Jamy · 1985 to 2026
$165.9M
Cellular Protein Involved in Trafficking of HIV-1R01GM111028 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI CARTER, CAROL A · 2013 to 2019
$2.0M
Structural Basis for HIV-1 Gag Interactions with Cellular ConstituentsR01GM117837 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SAAD, JAMIL SUBHI · 2015 to 2018
$1.7M
Gag Protein Interactions Important for HIV AssemblyR01GM048294 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI CARTER, CAROL A · 1993 to 2004
$1.5M
Cellular Protein Involved in Trafficking of HIV-1R01AI150489 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI CARTER, CAROL A · 2020 to 2022
$1.2M
Targeting Tsg101 to Identify Inhibitors of HIV-1 Budding by Experimental, Computational and Virtual ScreeningR21AI139036 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI CARTER, CAROL A, RIZZO, ROBERT C. · 2018 to 2019
$434k
NCI NIH HHS P30 CA013148NIAID NIH HHS R01 AI150489NIAID NIH HHS R21 AI139036NIGMS NIH HHS R01 GM048294NIGMS NIH HHS R01 GM111028NIGMS NIH HHS R01 GM117837
6 · The paper itself

Abstract

The Gag protein of avian sarcoma virus (ASV) lacks an

Indexed as

AnimalsAvian Sarcoma VirusesBinding SitesCell LineCell MembraneChickensChlorocebus aethiopsGene Products, gagHumansMembrane ProteinsMutationPhosphatidylinositol 4,5-DiphosphatePhospholipase C deltaProtein BindingProtein DomainsVirus ReleaseGene Products, gagMembrane ProteinsPhosphatidylinositol 4,5-DiphosphatePhospholipase C deltaASVavian sarcoma virusGag proteinhuman immunodeficiency virus (HIV)myristoylated matrixphosphatidylinositol 4,5-bisphosphate (PI(4,5)P2)plasma membraneprotein myristoylationprotein structureviral buddingvirus assembly

Identifiers

PMID30309982
PMCPMC6295721
OpenAlexW2896085252

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.