ArticleThe Plant cell2018
A Ycf2-FtsHi Heteromeric AAA-ATPase Complex Is Required for Chloroplast Protein Import.
Article in The Plant cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers.
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103 citing papers in PubMed, 195 citations in OpenAlex.
- YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana.FEBS open bio · 2026Article
- Deciphering the genetic basis of nodule number through integrative analysis of host genotype and endophytes.Journal of advanced research · 2026Article
- Comparative plastome analysis and plastomic phylogeny of Moraceae with expanded species-level sampling.BMC plant biology · 2026Article
- Comparative plastid genomics of Gastrochilus (Orchidaceae) with insights into molecular markers and phylogeny.BMC genomics · 2026Article
- New generic classification for Korean Peucedanum L. (Apiaceae) species based on deep phylogenomic study.BMC plant biology · 2026Article
- Progress and prospects of parasitic plant biodiversity genomics.Plant & cell physiology · 2026Review
- Functional Interaction Between Toc75 POTRA1 Domain and Tic22-III in the Intermembrane Space During Chloroplast Protein Import.Plant direct · 2026Article
- Correlated Evolutionary Rates Reveal Novel Components and Cross-Compartment Connectivity in Plant Proteostasis Systems.Genome biology and evolution · 2026Article
- Gene loss and positively selected genes in chloroplast genomes reveal adaptive evolution in Styracaceae.BMC plant biology · 2026Article
- Patterns of plastid gene evolution: identifying candidate genes for plastid-nuclear incompatibility across the Campanulaceae.Frontiers in plant science · 2026Article
- Chloroplast genome comparative analysis and phylogenetic relationships of 15 Syringa species (Oleaceae).Genetics and molecular biology · 2026Article
- Comparative complete chloroplast genome analysis ofFrontiers in plant science · 2026Article
- Reconstructing the evolutionary trajectory of Chamaelirium (Melanthiaceae) through phylogenomics: insights from plastome dynamics and historical biogeography.BMC plant biology · 2025Article
- Proteostasis and protein quality control in chloroplasts: mechanisms and novel insights related to protein mislocalization.Journal of experimental botany · 2025Review
- Substantial structural variation and repetitive DNA content contribute to intraspecific plastid genome evolution.BMC genomics · 2025Article
- Genome-wide identification and comprehensive analysis of the FtsH gene family in wheat.Molecular biology reports · 2025Article
- Comparative analyses of the organelle genomes inFrontiers in plant science · 2025Article
- Reduced plastid genomes of colorless facultative pathogens Prototheca (Chlorophyta) are retained for membrane transport genes.BMC biology · 2024Article
- Phylogenomics and adaptive evolution of hydrophytic umbellifers (tribe Oenantheae, Apioideae) revealed from chloroplast genomes.BMC plant biology · 2024Article
- Comparative Plastomics of Plantains (Plants (Basel, Switzerland) · 2024Article
43 more citing papers are in PubMed but not listed here.
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Authors and funding
13 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chloroplasts import thousands of nucleus-encoded preproteins synthesized in the cytosol through the TOC and TIC translocons on the outer and inner envelope membranes, respectively. Preprotein translocation across the inner membrane requires ATP; however, the import motor has remained unclear. Here, we report that a 2-MD heteromeric AAA-ATPase complex associates with the TIC complex and functions as the import motor, directly interacting with various translocating preproteins. This 2-MD complex consists of a protein encoded by the previously enigmatic chloroplast gene
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.