Evidence map›Paper›PMID 30309884›Full record

ArticleJournal of investigative medicine : the official publication of the American Federation for Clinical Research2019

Performance of the SteatoTest, ActiTest, NashTest and FibroTest in a multiethnic cohort of patients with type 2 diabetes mellitus.

Fernando Bril, Michael J McPhaul, Michael P Caulfield, Jean-Marie Castille, Thierry Poynard, Consuelo Soldevila-Pico, Virginia C Clark, Roberto J Firpi-Morell, Jinping Lai, Kenneth Cusi

Open access · hybridAbstract read
In one paragraph

Article in Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 4 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 4 syntheses or guidelines pooled it, 89 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Review
  11. Observational
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Noninvasive, Blood-Based Biomarkers as Screening Tools for Hepatic Fibrosis in People With Type 2 Diabetes.Clinical diabetes : a publication of the American Diabetes Association · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Fernando BrilDivision of Endocrinology, Diabetes and Metabolism, University of Florida, Gainesville, Florida, USA.ORCID 0000-0001-5570-4396
Michael J McPhaulQuest Diagnostics Nichols Institute, San Juan Capistrano, California, USA.
Michael P CaulfieldQuest Diagnostics Nichols Institute, San Juan Capistrano, California, USA.
Jean-Marie CastilleBiopredictive, Paris, France.
Thierry PoynardBiopredictive, Paris, France.
Consuelo Soldevila-PicoGastroenterology, Hepatology, and Nutrition, University of Florida, Gainesville, Florida, USA.
Virginia C ClarkGastroenterology, Hepatology, and Nutrition, University of Florida, Gainesville, Florida, USA.
Roberto J Firpi-MorellGastroenterology, Hepatology, and Nutrition, University of Florida, Gainesville, Florida, USA.
Jinping LaiDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida, USA.
Kenneth CusiDivision of Endocrinology, Diabetes and Metabolism, University of Florida, Gainesville, Florida, USA.
University of Florida · USQuest Diagnostics (United States) · USBiopredic (France) · FR

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

Fibromax is a diagnostic tool composed of the combination of 4 non-invasive biomarker panels for the diagnosis of steatosis (SteatoTest), necrosis and inflammation (ActiTest and NashTest-2) and fibrosis (FibroTest). The purpose of this study was to assess the performance of these biomarker panels in patients with type 2 diabetes mellitus (T2DM). All patients underwent routine labs, a 75 g oral glucose tolerance test, a liver proton magnetic resonance spectroscopy (

Indexed as

Diagnostic Techniques and ProceduresEthnicityBiomarkersCohort StudiesDiabetes Mellitus, Type 2FemaleHumansInflammationLiver CirrhosisMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseBiomarkersdiabetes mellitusfatty liverhepatitisinsulin

Identifiers

PMID30309884
PMCPMC6581087
OpenAlexW2897693155

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.