Evidence map›Paper›PMID 30309849›Full record

ArticleHaematologica2019

Finely-tuned regulation of AMP-activated protein kinase is crucial for human adult erythropoiesis.

Meriem Ladli, Cyrielle Richard, Lilia Cantero Aguilar, Sarah Ducamp, Sabrina Bondu, Pierre Sujobert, Jérôme Tamburini, Catherine Lacombe, Nabih Azar, Marc Foretz and 4 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Genetic adaptations shaping survival, pregnancy, and life at high altitude and sea level.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Meriem LadliInstitut Cochin, INSERM U1016.
Cyrielle RichardInstitut Cochin, INSERM U1016.
Lilia Cantero AguilarInstitut Cochin, INSERM U1016.
Sarah DucampInstitut Cochin, INSERM U1016.
Sabrina BonduInstitut Cochin, INSERM U1016.
Pierre SujobertInstitut Cochin, INSERM U1016.
Jérôme TamburiniInstitut Cochin, INSERM U1016.
Catherine LacombeInstitut Cochin, INSERM U1016.
Nabih AzarService d'Hémobiologie, Hôpital La Pitié Salpétrière, Paris, France.
Marc ForetzInstitut Cochin, INSERM U1016.
Yael ZermatiInstitut Cochin, INSERM U1016.
Patrick MayeuxInstitut Cochin, INSERM U1016.
Benoit ViolletInstitut Cochin, INSERM U1016.
Frédérique VerdierInstitut Cochin, INSERM U1016 frederique.verdier@inserm.fr.
Centre National de la Recherche Scientifique · FRInstitut Cochin · FRDélégation Paris 5 · FRInserm · FRPitié-Salpêtrière Hospital · FRSorbonne Paris Cité · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AMP-activated protein kinase (AMPK) is a heterotrimeric complex containing α, β, and γ subunits involved in maintaining integrity and survival of murine red blood cells. Indeed,

Indexed as

Cell DifferentiationErythropoiesisGene Expression Regulation, EnzymologicAdultAMP-Activated Protein KinasesAnimalsApoptosisAutophagyCells, CulturedEnzyme ActivationErythroblastsHumansMiceMice, KnockoutPhosphorylationRNA, Small InterferingAMP-Activated Protein KinasesRNA, Small Interfering

Identifiers

PMID30309849
PMCPMC6518903
OpenAlexW2897266519

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.