Evidence map›Paper›PMID 30309474›Full record

ReviewJournal of the American College of Cardiology2018

Stress Cardiomyopathy Diagnosis and Treatment: JACC State-of-the-Art Review.

Horacio Medina de Chazal, Marco Giuseppe Del Buono, Lori Keyser-Marcus, Liangsuo Ma, F Gerard Moeller, Daniel Berrocal, Antonio Abbate

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of the American College of Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05793008 (Characterization of priMary And sEcondary STress Related takOtsubo), which is not on this map. Cited by 287 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
287citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05793008 narecruitingnot on this mapstarted 2023, after this paper: background citation

Characterization of priMary And sEcondary STress Related takOtsubo: the MAESTRO Pilot Study

TypeinterventionalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2023 to 2026Enrolled60ConditionsTakotsubo Cardiomyopathy, Sepsis-induced CardiomyopathyArmsPositron Emission Tomography (PET) analysis, Blood samples collection, Clinical follow up visit
3 · Its place in the literature

Who cites it

287 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Review
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  15. Review
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  17. Article
  18. Exercise stress cardiomyopathy-a case report.European heart journal. Case reports · 2026
    Article
  19. Review
  20. Amphetamine-induced Reverse Takotsubo Cardiomyopathy and Thrombosis: A Case Report.Clinical practice and cases in emergency medicine · 2026
    Article

227 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Horacio Medina de ChazalVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia; Department of Cardiology, Hospital Italiano, Buenos Aires, Argentina.
Marco Giuseppe Del BuonoVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia; 'Dianne and C. Kenneth Wright' Center for Clinical and Translational Research, Virginia Commonwealth University, Richmond, Virginia.
Lori Keyser-Marcus'Dianne and C. Kenneth Wright' Center for Clinical and Translational Research, Virginia Commonwealth University, Richmond, Virginia.
Liangsuo MaInstitute of Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, Virginia.
F Gerard Moeller'Dianne and C. Kenneth Wright' Center for Clinical and Translational Research, Virginia Commonwealth University, Richmond, Virginia; Institute of Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, Virginia.
Daniel BerrocalDepartment of Cardiology, Hospital Italiano, Buenos Aires, Argentina.
Antonio AbbateVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia; 'Dianne and C. Kenneth Wright' Center for Clinical and Translational Research, Virginia Commonwealth University, Richmond, Virginia. Electronic address: antonio.abbate@vcuhealth.org.

Funding

Research Supplement to Promote Diversity in Health Related ResearchUL1TR002649 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2018 to 2022
$19.1M
NCATS NIH HHS UL1 TR002649
6 · The paper itself

Abstract

Stress cardiomyopathy is an acute reversible heart failure syndrome initially believed to represent a benign condition due to its self-limiting clinical course, but now recognized to be associated with a non-negligible rate of serious complications such as ventricular arrhythmias, systemic thromboembolism, and cardiogenic shock. Due to an increased awareness and recognition, the incidence of stress cardiomyopathy has been rising (15-30 cases per 100,000 per year), although the true incidence is unknown as the condition is likely underdiagnosed. Stress cardiomyopathy represents a form of neurocardiogenic myocardial stunning, and while the link between the brain and the heart is established, the exact pathophysiological mechanisms remain unclear. We herein review the proposed risk factors and triggers for the syndrome and discuss a practical approach to diagnosis and treatment of the patients with stress cardiomyopathy, highlighting potential challenges and unresolved questions.

Indexed as

Takotsubo CardiomyopathyDiagnostic ErrorsDisease ManagementHumansIncidenceRisk FactorscardiomyopathystressTakotsubo

Identifiers

PMID30309474
PMCPMC7058348

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.