Evidence map›Paper›PMID 30309465›Full record

ArticleJournal of the American College of Cardiology2018

Polygenic Risk Scoring for Coronary Heart Disease: The First Risk Factor.

Pradeep Natarajan

Abstract readEditorialComment
In one paragraph

Article in Journal of the American College of Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Prevention of atherosclerosis from childhood.Nature reviews. Cardiology · 2022
    Review
  12. Ten things to know about ten cardiovascular disease risk factors - 2022.American journal of preventive cardiology · 2022
    Review
  13. Clinical utility of polygenic risk scores for coronary artery disease.Nature reviews. Cardiology · 2022 · on this map
    Review
  14. Review
  15. Review
  16. Article
  17. Ten things to know about ten cardiovascular disease risk factors.American journal of preventive cardiology · 2021
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Pradeep NatarajanCardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts; and the Department of Medicine, Harvard Medical School, Boston, Massachusetts. Electronic address: pnatarajan@mgh.harvard.edu.

Funding

Understanding modifiers of mendelian mutation penetrance using familial hypercholesterolemia as a modelK08HL140203 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NATARAJAN, PRADEEP · 2018 to 2019
$343k
NHLBI NIH HHS K08 HL140203
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Coronary Artery DiseaseAdultGenomicsHumansMultifactorial InheritancePrimary PreventionRisk Factorscoronary artery diseasegenomic risk predictionprimary prevention

Identifiers

PMID30309465
PMCPMC6215449

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.