Evidence map›Paper›PMID 30309373›Full record

SynthesisScandinavian journal of trauma, resuscitation and emergency medicine2018

The effect of bystander cardiopulmonary resuscitation on the survival of out-of-hospital cardiac arrests: a systematic review and meta-analysis.

Jianting Song, Wenxiu Guo, Xiaoguang Lu, Xin Kang, Yi Song, Dianbo Gong

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Scandinavian journal of trauma, resuscitation and emergency medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06530433 (Evaluation of an Enhanced Community First Responder Support System to Improve Bystander Cardiopulmonary Resuscitation Quality for Patients Experiencing Out-of-hospital Cardiac Arrest), which is not on this map. Cited by 54 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06530433 narecruitingnot on this mapstarted 2024, after this paper: background citation

Evaluation of an Enhanced Community First Responder Support System to Improve Bystander Cardiopulmonary Resuscitation Quality for Patients Experiencing Out-of-hospital Cardiac Arrest

TypeinterventionalSponsorSingapore General HospitalRan2024 to 2028Enrolled165ConditionsOut-Of-Hospital Cardiac ArrestArmsCPRCard + TCPR Link App and Web, CPRCard Only
3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. How to evaluate first aid skills after training: a systematic review.Scandinavian journal of trauma, resuscitation and emergency medicine · 2022
    Pooled it
  3. Pooled it
  4. Pooled it
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  6. Trial
  7. Article
  8. Article
  9. Bystander interventions and their impact on road injury outcomes: a scoping review.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025
    Review
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  11. Article
  12. Observational
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  16. Review
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  19. Article
  20. Automatic external defibrillator (AED) location - seconds that save lifes.Archives of public health = Archives belges de sante publique · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jianting SongDalian Medical University, No. 9, west section, Lushun South road, Dalian city, Liaoning Province, China.
Wenxiu GuoLiaoning university of Traditional Chinese Medicine, No. 79, Chongshan road, Huanggu District, Shenyang city, Liaoning province, China.
Xiaoguang LuDepartment of Emergency Medicine, Affiliated Zhongshan Hospital of Dalian University, No. 6th Jiefang Street, ZhongShan District, Dalian city, Liaoning Province, China. dllxg@126.com.ORCID http://orcid.org/0000-0001-8741-9928
Xin KangDepartment of Emergency Medicine, Affiliated Zhongshan Hospital of Dalian University, No. 6th Jiefang Street, ZhongShan District, Dalian city, Liaoning Province, China.
Yi SongDepartment of Emergency Medicine, Affiliated Zhongshan Hospital of Dalian University, No. 6th Jiefang Street, ZhongShan District, Dalian city, Liaoning Province, China.
Dianbo GongDepartment of Emergency Medicine, Affiliated Zhongshan Hospital of Dalian University, No. 6th Jiefang Street, ZhongShan District, Dalian city, Liaoning Province, China.

Funding

Natural Science Foundation of China (NSFC) 81173397Natural Science Foundation of China (NSFC) 81473512Natural Science Foundation of China (NSFC) 81673801
6 · The paper itself

Abstract

backgroundFor many years, bystander cardiopulmonary resuscitation (BCPR) has been considered as a favorable factor to improve survival of out-of-hospital cardiac arrests (OHCAs). To examine the effect of BCPR on the survival of OHCAs and whether BCPR might also improve survival when the initial rhythm of OHCAs is limited, we performed a meta-analysis on published observational studies.

methodsWe did a systematic review to identify all studies published up to March, 2018, in any language, that reported the relation between BCPR and the survival of OHCAs. Using standard forms, two authors independently identified studies for inclusion and extracted information. The outcome was survival. Meta-regression was done to ascertain weighted factors for the outcomes.

resultsData were extracted from 19 studies involving 232,703 patients. Firstly, pooled odds ratio (OR) from 16 cohort studies showed that BCPR was associated with improved chance of survival of OHCAs compared with NO-BCPR (OR 1.95, 95% confidence interval [CI]: 1.66-2.30). Secondly, from 8 cohort studies of OHCAs whose initial rhythm is limited, the pooled OR was 2.10 (95% CI, 1.68-2.63) of 6 articles for shockable rhythm and 1.07 (95% CI, 0.37-3.13) of 2 articles for non-shockable rhythm. Meta-regression showed a relation between the survival of OHCAs and BCPR was influenced by area (p < 0.05).

conclusionsBased on currently available evidence, the findings of this meta-analysis suggest that BCPR increases the survival of OHCAs, and it also help OHCAs whose initial rhythm is shockable. That is to say BCPR is also helpful when emergency department response time is short. Therefore global priority should be given to increasing the incidence of BCPR by evidence-based best practice.

Indexed as

Cardiopulmonary ResuscitationSurvival AnalysisHumansOut-of-Hospital Cardiac ArrestBystander CPRInitial rhythmMeta-analysisOut-of-hospital cardiac arrest

Identifiers

PMID30309373
PMCPMC6182861

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.