Evidence map›Paper›PMID 30309357›Full record

ArticleLipids in health and disease2018

The prevalence of hyperuricemia and its correlates in Ganzi Tibetan Autonomous Prefecture, Sichuan Province, China.

Xin Zhang, Qingtao Meng, Jiayue Feng, Hang Liao, Rufeng Shi, Di Shi, Lachu Renqian, Zeren Langtai, Yuanbin Diao, Xiaoping Chen

Abstract read
In one paragraph

Article in Lipids in health and disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

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26citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  14. Acute oral toxicity assessment and anti-hyperuricemic activity ofSaudi journal of biological sciences · 2022
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Xin ZhangDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610000, People's Republic of China.
Qingtao MengDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610000, People's Republic of China.
Jiayue FengDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610000, People's Republic of China.
Hang LiaoDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610000, People's Republic of China.
Rufeng ShiDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610000, People's Republic of China.
Di ShiDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610000, People's Republic of China.
Lachu RenqianJiulong County People's Hospital, Jiulong, 616200, Tibetan Autonomous Prefecture, People's Republic of China.
Zeren LangtaiJiulong County People's Hospital, Jiulong, 616200, Tibetan Autonomous Prefecture, People's Republic of China.
Yuanbin DiaoGanzi Tibetan Autonomous Prefecture People's Hospital, Kangding, 626000, Tibetan Autonomous Prefecture, People's Republic of China.
Xiaoping ChenDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610000, People's Republic of China. xiaopingchen111@126.com.

Funding

Science and Technology Pillar Programs in Sichuan Province 2012SZ0131Science and Technology Pillar Programs in Sichuan Province 2017SZ0008
6 · The paper itself

Abstract

backgroundHyperuricemia is a common and serious public health problem. There has been no broad epidemiological survey of hyperuricemia in China, especially in Tibetan area. This study was therefore investigated the prevalence of hyperuricemia and its correlated factors among people aged 18-85 years in Ganzi Tibetan Autonomous Prefecture, Sichuan Province, China.

methodsWe carried out a cross-sectional study among 3093 participants in Ganzi Tibetan Autonomous Prefecture using questionnaires in face-to-face interviews, anthropometric measurements and biochemical tests. We included 1416 subjects with complete data including serum uric acid and medical history to analyze the prevalence of hyperuricemia and correlated factors. Hyperuricemia was defined as a fasting serum uric acid level higher than 420 μmol/L in men and 360 μmol/L in women.

resultsThe overall crude prevalence of hyperuricemia was 37.2%, and was greater in men than women (41% vs 34.4%, P = 0.011). The age-adjusted prevalence was 33.0%. Characteristics linked to hyperuricemia were farmers-herdsmen (OR: 1.749, 95% CI: 1.022-2.992), low to moderate education level (low OR:1.57, 95% CI: 1.102-2.237; moderate OR: 1.86, 95% CI: 1.167-2.963), current drinking (OR: 1.795, 95% CI: 1.193-2.702), hypertension (OR: 1.48, 95% CI: 1.091-2.006), higher body mass index (1 unit increase) (OR: 1.116, 95% CI: 1.077-1.156) and higher serum creatinine (1 unit increase) (OR: 1.046, 95% CI: 1.034-1.059). Serum uric acid was positively related to triglycerides and total cholesterol and negatively related to high density lipoprotein cholesterol in all subjects. Hyperuricemia was a risk factor for high triglyceride ((OR: 2.13, 95% CI: 1.156-3.9266) and high total cholesterol (OR: 2.313, 95% CI: 1.364-3.923) in men and for high low-density lipoprotein cholesterol (OR: 2.696, 95% CI: 1.386-5.245) in women.

conclusionThere is a high prevalence of hyperuricemia in Ganzi Tibetan Autonomous Prefecture. The government needs to prevent and manage hyperuricemia in this area.

Indexed as

DyslipidemiasAdolescentAdultAgedAged, 80 and overCholesterolCross-Sectional StudiesFemaleHumansHyperuricemiaMaleMiddle AgedPrevalenceTibetTriglyceridesUric AcidCholesterolTriglyceridesUric AcidHyperuricemiaPrevalenceRiskTibetTibetanUric acid

Identifiers

PMID30309357
PMCPMC6182831

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.