Evidence map›Paper›PMID 30309353›Full record

ArticleBMC medical genomics2018

Privacy-preserving record linkage in large databases using secure multiparty computation.

Peeter Laud, Alisa Pankova

Abstract read
In one paragraph

Article in BMC medical genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review of Clinical Research Informatics.Yearbook of medical informatics · 2020
    Review
  8. Fold-stratified cross-validation for unbiased and privacy-preserving federated learning.Journal of the American Medical Informatics Association : JAMIA · 2020
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Peeter LaudCybernetica AS, Ülikooli 2, Tartu, 51003, Estonia. peeter@cyber.ee.
Alisa PankovaCybernetica AS, Ülikooli 2, Tartu, 51003, Estonia.

Funding

SERGEANT: SEcuRe GEnome Analysis competitionR13HG009072 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JIANG, XIAOQIAN, OHNO-MACHADO, LUCILA · 2016 to 2019
$65k
NHGRI NIH HHS R13 HG009072
6 · The paper itself

Abstract

backgroundPractical applications for data analysis may require combining multiple databases belonging to different owners, such as health centers. The analysis should be performed without violating privacy of neither the centers themselves, nor the patients whose records these centers store. To avoid biased analysis results, it may be important to remove duplicate records among the centers, so that each patient's data would be taken into account only once. This task is very closely related to privacy-preserving record linkage.

methodsThis paper presents a solution to privacy-preserving deduplication among records of several databases using secure multiparty computation. It is build upon one of the fastest practical secure multiparty computation platforms, called Sharemind.

resultsThe tests on ca 10 million records of simulated databases with 1000 health centers of 10000 records each show that the computation is feasible in practice. The expected running time of the experiment is ca. 30 min for computing servers connected over 100 Mbit/s WAN, the expected error of the results is 2

conclusionsThe solution is ready for practical use. It has well-defined security properties, implied by the properties of Sharemind platform. The solution assumes that exact matching of records is required, and a possible future research would be extending it to approximate matching.

Indexed as

AlgorithmsComputer SecurityDatabases, FactualDeduplicationPrivacyPrivacy-preserving record linkageSecure multiparty computation

Identifiers

PMID30309353
PMCPMC6180364

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.