Evidence map›Paper›PMID 30309342›Full record

Observational studyBMC nephrology2018

Design and methodology of the screening for CKD among older patients across Europe (SCOPE) study: a multicenter cohort observational study.

Andrea Corsonello, Lisanne Tap, Regina Roller-Wirnsberger, Gerhard Wirnsberger, Carmine Zoccali, Tomasz Kostka, Agnieszka Guligowska, Francesco Mattace-Raso, Pedro Gil, Lara Guardado Fuentes and 11 more

Registry-linked trialOpen access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMC nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02691546 (Screening for Chronic Kidney Disease), which is not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02691546 completednot on this map

Screening for Chronic Kidney Disease (CKD) Among Older People Across Europe (SCOPE)

TypeobservationalSponsorIstituto Nazionale di Ricovero e Cura per AnzianiRan2016 to 2020Enrolled2,434ConditionsChronic Kidney DiseasesArmsblood sample collection
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 28 citations in OpenAlex.

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  12. Validation of the German version of the Protein Screener 55.European journal of clinical nutrition · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 11 institutions in 8 countries.

Andrea CorsonelloItalian National Research Center on Aging (INRCA), Ancona, Fermo and Cosenza, Italy.
Lisanne TapSection of Geriatric Medicine, Department of Internal Medicine, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
Regina Roller-WirnsbergerDepartment of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria. Regina.Roller-Wirnsberger@medunigraz.at.ORCID 0000-0002-1273-6520
Gerhard WirnsbergerDepartment of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria.
Carmine ZoccaliCNR-IFC, Clinical Epidemiology and Pathophysiology of Hypertension and Renal Diseases, Ospedali Riuniti, Reggio Calabria, Italy.
Tomasz KostkaDepartment of Geriatrics, Healthy Ageing Research Centre, Medical University of Lodz, Lodz, Poland.
Agnieszka GuligowskaDepartment of Geriatrics, Healthy Ageing Research Centre, Medical University of Lodz, Lodz, Poland.
Francesco Mattace-RasoSection of Geriatric Medicine, Department of Internal Medicine, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
Pedro GilDepartment of Geriatric Medicine, Hospital Clinico San Carlos, Madrid, Spain.
Lara Guardado FuentesDepartment of Geriatric Medicine, Hospital Clinico San Carlos, Madrid, Spain.
Itshak MeltzerThe Recanati School for Community Health Professions at the faculty of Health Sciences, Ben-Gurion University of the Negev, Beersheba, Israel.
Ilan YehoshuaMaccabi Healthcare Services Southern Region, Tel Aviv, Israel.
Francesc Formiga-PerezGeriatric Unit, Internal Medicine Department and Nephrology Department, Bellvitge University Hospital - IDIBELL - L'Hospitalet de Llobregat, Barcelona, Spain.
Rafael Moreno-GonzálezGeriatric Unit, Internal Medicine Department and Nephrology Department, Bellvitge University Hospital - IDIBELL - L'Hospitalet de Llobregat, Barcelona, Spain.
Christian WeingartDepartment of General Internal Medicine and Geriatrics, Krankenhaus Barmherzige Brüder Regensburg and Institute for Biomedicine of Aging, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Ellen FreibergerDepartment of General Internal Medicine and Geriatrics, Krankenhaus Barmherzige Brüder Regensburg and Institute for Biomedicine of Aging, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Johan ÄrnlövDepartment of Medical Sciences, Uppsala University, Uppsala, Sweden.
Axel C CarlssonDepartment of Medical Sciences, Uppsala University, Uppsala, Sweden.
Silvia BustacchiniItalian National Research Center on Aging (INRCA), Ancona, Fermo and Cosenza, Italy.
Fabrizia LattanzioItalian National Research Center on Aging (INRCA), Ancona, Fermo and Cosenza, Italy.
SCOPE investigators
Erasmus MC · NLIstituto Nazionale di Riposo e Cura per Anziani · ITMedical University of Graz · ATBellvitge University Hospital · ESBen-Gurion University of the Negev · ILFriedrich-Alexander-Universität Erlangen-Nürnberg · DEUppsala University · SEDalarna University · SEHospital Clínico San Carlos · ESMedical University of Lodz · PLOspedali Riuniti di Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDecline of renal function is common in older persons and the prevalence of chronic kidney disease (CKD) is rising with ageing. CKD affects different outcomes relevant to older persons, additionally to morbidity and mortality which makes CKD a relevant health burden in this population. Still, accurate laboratory measurement of kidney function is under debate, since current creatinine-based equations have a certain degree of inaccuracy when used in the older population. The aims of the study are as follows: to assess kidney function in a cohort of 75+ older persons using existing methodologies for CKD screening; to investigate existing and innovative biomarkers of CKD in this cohort, and to align laboratory and biomarker results with medical and functional data obtained from this cohort. The study was registered at ClinicalTrials.gov, identifier NCT02691546, February 25th 2016. METHODS/

designAn observational, multinational, multicenter, prospective cohort study in community dwelling persons aged 75 years and over, visiting the outpatient clinics of participating institutions. The study will enroll 2450 participants and is carried out in Austria, Germany, Israel, Italy, the Netherlands, Poland and Spain. Participants will undergo clinical and laboratory evaluations at baseline and after 12 and 24 months- follow-up. Clinical evaluation also includes a comprehensive geriatric assessment (CGA). Local laboratory will be used for 'basic' parameters (including serum creatinine and albumin-to-creatinine ratio), whereas biomarker assessment will be conducted centrally. An intermediate telephone follow-up will be carried out at 6 and 18 months. DISCUSSION: Combining the use of CGA and the investigation of novel and existing independent biomarkers within the SCOPE study will help to provide evidence in the development of European guidelines and recommendations in the screening and management of CKD in older people.

trial registrationThis study was registered prospectively on the 25th February 2016 at clinicaltrials.gov ( NCT02691546 ).

Indexed as

Geriatric AssessmentMass ScreeningAgedAlbuminuriaBiomarkersClinical ProtocolsCreatinineEuropeGlomerular Filtration RateHumansProspective StudiesRenal Insufficiency, ChronicBiomarkersCreatinineAgeingChronic kidney diseaseDisabilityFrailtyOlder people

Identifiers

PMID30309342
PMCPMC6180570
OpenAlexW2895918911

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.