Evidence map›Paper›PMID 30309234›Full record

ArticleJournal of stroke2018

Prognosis of Acute Intracranial Atherosclerosis-Related Occlusion after Endovascular Treatment.

Jin Soo Lee, Seong-Joon Lee, Joon Sang Yoo, Jeong-Ho Hong, Chang-Hyun Kim, Yong-Won Kim, Dong-Hun Kang, Yong-Sun Kim, Ji Man Hong, Jin Wook Choi and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of stroke, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 3 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 3 syntheses or guidelines pooled it, 121 citations in OpenAlex.

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  15. Comparative analysis of outcome-associated factors following endovascular treatment for intracranial atherosclerotic disease and cardioembolism: A subanalysis of the K-NET registry.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 3 countries.

Jin Soo LeeDepartment of Neurology, Ajou University Medical Center, Ajou University School of Medicine, Suwon, Korea.
Seong-Joon LeeDepartment of Neurology, Ajou University Medical Center, Ajou University School of Medicine, Suwon, Korea.
Joon Sang YooDepartment of Neurology, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.
Jeong-Ho HongDepartment of Neurology, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.
Chang-Hyun KimDepartment of Neurosurgery, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.
Yong-Won KimDepartment of Neurology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.
Dong-Hun KangDepartment of Radiology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.
Yong-Sun KimDepartment of Radiology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.
Ji Man HongDepartment of Neurology, Ajou University Medical Center, Ajou University School of Medicine, Suwon, Korea.
Jin Wook ChoiDepartment of Radiology, Ajou University Medical Center, Ajou University School of Medicine, Suwon, Korea.
Bruce OvbiageleDepartment of Neurology, Medical University of South Carolina, Charleston, SC, USA.
Andrew M DemchukDepartment of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
Sung-Il SohnDepartment of Neurology, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.
Yang-Ha HwangDepartment of Neurology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.
Ajou University · KRKyungpook National University Hospital · KRKeimyung University Dongsan Medical Center · KRKeimyung University · KRMedical University of South Carolina · USUniversity of Calgary · CA

Funding

Ministry of Science and Technology 2014R1A5A2010008Ministry of Science and Technology 2018R1A2B6007094National Research Foundation of Korea
6 · The paper itself

Abstract

background and purposeLittle is known about prognosis after endovascular therapy (EVT) for acute large artery occlusion (LAO) caused by underlying intracranial atherosclerotic stenosis (ICAS). Therefore, we investigated the prognosis following EVT according to the underlying etiology of LAO.

methodsPatients from the Acute Stroke due to Intracranial Atherosclerotic occlusion and Neurointervention-Korean Retrospective (ASIAN KR) registry (n=720) were included if their occlusion was in the intracranial anterior circulation and their onset-to-puncture time was <24 hours. Occlusion was classified according to etiology as follows: no significant stenosis after recanalization (Embolic group), and fixed significant focal stenosis in the occlusion site with flow impairment or re-occlusion observed during EVT (ICAS group). Patients were excluded when significant extracranial carotid lesions existed, and when the intracranial occlusion was intractable to EVT so that the etiology was undetermined. The effect of angiographic etiologic classification on outcomes was evaluated using multivariable analysis that was adjusted for potential confounders.

resultsAmong eligible patients (n=520), 421 and 99 were classified in the Embolic and ICAS groups, respectively. Patients in the Embolic and ICAS groups had similar successful reperfusion rates with EVT (79.6% vs. 76.8%, P=0.537) and 3-month functional independence (54.5% vs. 45.5%, P=0.104). In multivariable analysis, ICAS-related occlusion (odds ratio, 0.495; 95% confidence interval, 0.269 to 0.913; P=0.024) showed poorer 3-month functional independence compared to embolic occlusion.

conclusions After EVT, patients with acute ICAS-related occlusion have relatively poor functional outcomes compared to those with embolic occlusion. Novel strategies need to be developed to improve EVT outcomes for ICAS occlusion.

Indexed as

AtherosclerosisCerebral infarctionEmbolismReperfusionThrombectomyTreatment outcome

Identifiers

PMID30309234
PMCPMC6186924
OpenAlexW2894573184

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.