Evidence map›Paper›PMID 30308960›Full record

ArticleMolecules (Basel, Switzerland)2018

A New Protocol for the Synthesis of New Thioaryl-Porphyrins Derived from 5,10,15,20-Tetrakis(pentafluorophenyl)porphyrin: Photophysical Evaluation and DNA-Binding Interactive Studies.

Patrícia Foletto, Fabiula Correa, Luciano Dornelles, Bernardo A Iglesias, Carolina H da Silveira, Pablo A Nogara, João B T da Rocha, Maria A F Faustino, Oscar E D Rodrigues

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Patrícia FolettoDepartamento de Química, Universidade Federal de Santa Maria, Santa Maria-RS 97105-900, Brazil. patriciafoletto@hotmail.com.
Fabiula CorreaDepartamento de Química, Universidade Federal de Santa Maria, Santa Maria-RS 97105-900, Brazil. fabiulacorrea11@gmail.com.
Luciano DornellesDepartamento de Química, Universidade Federal de Santa Maria, Santa Maria-RS 97105-900, Brazil. ldornel@gmail.com.
Bernardo A IglesiasLaboratório de Bioinorgânica e Materiais Porfirínicos, Departamento de Química, Universidade Federal de Santa Maria⁻UFSM, Santa Maria⁻RS 97105-900, Brazil. bernardopgq@gmail.com.ORCID 0000-0002-4039-6316
Carolina H da SilveiraLaboratório de Bioinorgânica e Materiais Porfirínicos, Departamento de Química, Universidade Federal de Santa Maria⁻UFSM, Santa Maria⁻RS 97105-900, Brazil. carolinahahndasilveira@gmail.com.
Pablo A NogaraLaboratório de Bioquímica Toxicológica, Departamento de Bioquímica e Biologia Molecular, Univerisidade Federal de Santa Maria, Santa Maria⁻RS 97105-900, Brazil. pbnogara@gmail.com.
João B T da RochaLaboratório de Bioquímica Toxicológica, Departamento de Bioquímica e Biologia Molecular, Univerisidade Federal de Santa Maria, Santa Maria⁻RS 97105-900, Brazil. jbtrocha@yahoo.com.br.
Maria A F FaustinoQOPNA and Department of Chemistry, University of Aveiro, Aveiro 3810-193, Portugal. faustino@ua.pt.
Oscar E D RodriguesDepartamento de Química, Universidade Federal de Santa Maria, Santa Maria-RS 97105-900, Brazil. rodriguesoed@smail.ufsm.br.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico Ed. Universal 400791/2016-1Conselho Nacional de Desenvolvimento Científico e Tecnológico Pesquisador visitante-401397/2014-9Conselho Nacional de Desenvolvimento Científico e Tecnológico Produtividade em Pesquisa-303387/2015-7
6 · The paper itself

Abstract

A new protocol for the preparation of thioaryl-porphyrins is described. The compounds were prepared from different disulfides employing NaBH₄ as a reducing agent. The methodology allowed the preparation of four different thioaryl-porphyrins in very-good to excellent yields under soft conditions, such as short reaction times and smooth heating. Additionally, the photophysical properties of new compounds were determined and experimental and theoretical DNA interactions were assessed.

Indexed as

LightDNAFluorobenzenesFluorocarbonsKineticsMolecular Docking SimulationPorphyrinsQuantum TheorySinglet OxygenSpectrometry, FluorescenceSpectrophotometry, UltravioletDNAFluorobenzenesFluorocarbonsmeso-tetra(pentafluorophenyl)porphyrinPorphyrinsSinglet OxygendisulfidesDNA interactionphotophysical characterizationthioaryl-porphyrins

Identifiers

PMID30308960
PMCPMC6222446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.