Evidence map›Paper›PMID 30308959›Full record

ArticleJournal of clinical medicine2018

The Comparative Associations of Ultrasound and Computed Tomography Estimates of Muscle Quality with Physical Performance and Metabolic Parameters in Older Men.

Michael O Harris-Love, Nilo A Avila, Bernadette Adams, June Zhou, Bryant Seamon, Catheeja Ismail, Syed H Zaidi, Courtney A Kassner, Frank Liu, Marc R Blackman

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02350465 (Detection and Treatment of Sarcopenia and Myosteatosis in Older African Americans), which is not on this map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02350465 naunknown statusnot on this map

Detection and Treatment of Sarcopenia and Myosteatosis in Older African Americans

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2015 to 2023Enrolled136ConditionsSarcopeniaArmsEccentric Exercise, Concentric Exercise
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Observational
  6. Article
  7. Poor muscle quality: A hidden and detrimental health condition in obesity.Reviews in endocrine & metabolic disorders · 2025
    Review
  8. What Is 'Muscle Health'? A Narrative Review and Conceptual Framework.Journal of functional morphology and kinesiology · 2025
    Review
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Michael O Harris-LoveMuscle Morphology, Mechanics, and Performance Laboratory, Geriatrics Service, Veterans Affairs Medical Center, Washington, DC 20422, USA. mhl@gwu.edu.ORCID 0000-0002-1842-3269
Nilo A AvilaRadiology Service, Veterans Affairs Medical Center, Washington, DC 20422, USA. nilo.avila@nih.gov.
Bernadette AdamsMuscle Morphology, Mechanics, and Performance Laboratory, Geriatrics Service, Veterans Affairs Medical Center, Washington, DC 20422, USA. blpadams@gmail.com.
June ZhouResearch Service, Veterans Affairs Medical Center, Washington, DC 20422, USA. June.Zhou@va.gov.
Bryant SeamonMuscle Morphology, Mechanics, and Performance Laboratory, Geriatrics Service, Veterans Affairs Medical Center, Washington, DC 20422, USA. seamon@musc.edu.ORCID 0000-0002-3995-1052
Catheeja IsmailMuscle Morphology, Mechanics, and Performance Laboratory, Geriatrics Service, Veterans Affairs Medical Center, Washington, DC 20422, USA. 34Cath@gmail.com.
Syed H ZaidiRadiology Service, Veterans Affairs Medical Center, Washington, DC 20422, USA. Syed.Zaidi2@va.gov.
Courtney A KassnerRadiology Service, Veterans Affairs Medical Center, Washington, DC 20422, USA. Courtney.Kassner@va.gov.
Frank LiuNuclear Medicine Section, Veterans Affairs Medical Center, Washington, DC 20422, USA. Frank.Liu2@va.gov.
Marc R BlackmanResearch Service, Veterans Affairs Medical Center, Washington, DC 20422, USA. Marc.Blackman@va.gov.
Morpho (United States) · USVeterans Health Administration · USGeorgetown University · USGeorge Washington University · USMilken Institute · USNational Institutes of Health · US

Funding

Maternal Morbidity and Mortality: Risk Factors, Early Detection and Personalized InterventionUL1TR001409 · NCATS · GEORGETOWN UNIVERSITY · PI GONDRE-LEWIS, MARJORIE C, MELLMAN, THOMAS A · 2015 to 2024
$37.8M
Georgetown-Howard Universities Center for Clinical and Translational Science (GHUUL1TR000101 · NCATS · GEORGETOWN UNIVERSITY · PI MELLMAN, THOMAS A, VERBALIS, JOSEPH G · 2012 to 2015
$19.3M
Detection and Treatment of Sarcopenia and Myosteatosis in Older African AmericansIK2RX001854 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI HARRIS-LOVE, MICHAEL · 2015 to 2020
–
National Center for Advancing Translational Sciences UL1TR000101NCATS NIH HHS UL1 TR000101NCATS NIH HHS UL1 TR001409RRD VA IK2 RX001854U.S. Department of Veterans Affairs 1IK2RX001854VA Capitol Health Care Network Pilot Grant Program VISN 5; VA Station: 688
6 · The paper itself

Abstract

Estimates of muscle tissue composition may have greater prognostic value than lean body mass levels regarding health-related outcomes. Ultrasound provides a relatively low cost, safe, and accessible mode of imaging to assess muscle morphology. The purpose of this study was to determine the construct validity of muscle echogenicity as a surrogate measure of muscle quality in a sample of older, predominantly African American (AA) participants. We examined the association of rectus femoris echogenicity with mid-thigh computed tomography (CT) scan estimates of intra- and intermuscular adipose tissue (IMAT), basic metabolic parameters via blood sample analysis, muscle strength, and mobility status. This observational study was conducted at a federal medical center and included 30 community-dwelling men (age, 62.5 ± 9.2; AA,

Indexed as

agingcomputed tomographyechogenicitymetabolic statusmuscle qualitymuscle strengthmuscle tissue compositionmyosteatosisquantitative ultrasoundsarcopenia

Identifiers

PMID30308959
PMCPMC6210142
OpenAlexW2896705252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.