ArticlePsychosomatic medicine2019
Marriage and Gut (Microbiome) Feelings: Tracing Novel Dyadic Pathways to Accelerated Aging.
Article in Psychosomatic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 40 citations in OpenAlex.
- Microbes, mood, and metabolism/obesity: Pharmacological insights into the gut-obesity-depression triad.Cellular and molecular life sciences : CMLS · 2026Review
- Negative social ties as emerging risk factors for accelerated aging, inflammation, and multimorbidity.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Vitamin D status andFrontiers in nutrition · 2026Article
- Association of unhealthy lifestyle and the risk of type 2 diabetes mellitus with arthritis in middle-aged and elderly Chinese individuals: evidence from the CHARLS.Aging clinical and experimental research · 2025Article
- Association between the dietary index of gut microbiota and abnormal bowel symptoms in U.S. adults: a cross-sectional study based on NHANES 2007-2010.BMC gastroenterology · 2025Article
- The Impact of Health-Promoting Lifestyle Behaviors on Gut Microbiota in Survivors of Hematological Cancer: A Scoping Review.Cancer reports (Hoboken, N.J.) · 2025Article
- The relationship between night eating behavior, gastrointestinal symptoms, and psychological well-being: insights from a cross-sectional study in Türkiye.Journal of eating disorders · 2025Article
- Obesity-associated memory impairment and neuroinflammation precede widespread peripheral perturbations in aged rats.Immunity & ageing : I & A · 2025Article
- Comprehensive assessment of cellular senescence in intestinal immunity and biologic therapy response in ulcerative colitis.Scientific reports · 2024Article
- Couples in breast cancer survivorship: Daily associations in relationship satisfaction, stress, and health.Comprehensive psychoneuroendocrinology · 2024Article
- The Interaction of Positive and Negative Relationship Characteristics and Their Association with Relationship and Individual Health Outcomes in Older Couples.Behavioral sciences (Basel, Switzerland) · 2024Article
- The post-Cartesian dilemma: Reuniting the mind and body through psychoneuroimmunology.Comprehensive psychoneuroendocrinology · 2024Article
- Psychosocial and biological pathways to aging : The role(s) of the behavioral and social sciences in geroscience.Zeitschrift fur Gerontologie und Geriatrie · 2024Review
- Moving toward affective immunology: Legacy and future directions.Comprehensive psychoneuroendocrinology · 2024Article
- Turning stress into success: A festschrift in honor of Janice Kiecolt-Glaser.Comprehensive psychoneuroendocrinology · 2024Article
- A social science: Using psychoneuroimmunology principles to promote career longevity, productivity, and meaning.Comprehensive psychoneuroendocrinology · 2024Article
- Relationship Functioning and Gut Microbiota Composition among Older Adult Couples.International journal of environmental research and public health · 2023Article
- The gut connection: Intestinal permeability as a pathway from breast cancer survivors' relationship satisfaction to inflammation across treatment.Brain, behavior, and immunity · 2022Article
- The gut microbiota and nervous system: Age-defined and age-defying.Seminars in cell & developmental biology · 2021Article
- Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention.Signal transduction and targeted therapy · 2021Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Within a couple, partners influence each other's mental and physical health. This review focuses on how couples' relationships, the partners' individual and joint vulnerabilities, and their health behaviors influence health through changes in the gut microbiota, metabolism, and immune function. Couples' shared stressors and emotions and their intertwined lifestyles and routines serve to promote common disease risks in part through parallel changes in their gut microbiotas. Marital discord, stress, and depression have strong bidirectional links, fueling one another. Chronic marital stress and depression can elevate the risk for obesity, metabolic syndrome, and cardiovascular disease by altering resting energy expenditure, insulin production, and triglyceride responses after unhealthy meals. During stressful times, health behaviors typically suffer-and sleep disturbances, poor diets, and sedentary behavior all influence these metabolic pathways while also promoting gut dysbiosis. Dysbiosis increases intestinal permeability (gut leakiness), providing a mechanistic pathway from marital distress and depression to heightened inflammation and accelerated aging. Age-related changes in the gut microbiota's composition and gut leakiness foster immunosenescence, as well as the progression of inflamm-aging; these age-related risks may be altered by stress and depression, diet, sleep, exercise habits, and developmental shifts in emotion regulation strategies. Consideration of the strong mutual influences that partners have on each other's mood and health behaviors, as well as the biological pathways that underlie these influences, provides a new way to view marriage's health implications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.