Evidence map›Paper›PMID 30308464›Full record

ArticlePsychiatry research2018

Intimate partner violence moderates the association between oxytocin and reactivity to dyadic conflict among couples.

Amber M Jarnecke, Eileen Barden, Sudie E Back, Kathleen T Brady, Julianne C Flanagan

Abstract read
In one paragraph

Article in Psychiatry research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Amber M JarneckeDepartment of Psychiatry & Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA. Electronic address: jarnecka@musc.edu.
Eileen BardenDepartment of Psychology, Binghamton University - State University of New York, Binghamton, NY, USA.
Sudie E BackDepartment of Psychiatry & Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA; Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC, USA.
Kathleen T BradyDepartment of Psychiatry & Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA; Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC, USA.
Julianne C FlanaganDepartment of Psychiatry & Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA.
Medical University of South Carolina · USBinghamton University · USRalph H. Johnson VA Medical Center · US

Funding

TRAINING IN ALCOHOL TREATMENT RESEARCHT32AA007474 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI John J. Woodward · 1987 to 2026
$8.5M
Interdisciplinary Women's Health Research at MUSCK12HD055885 · NICHD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI MCGINTY, JACQUELINE F. · 2007 to 2021
$7.2M
Integrating Neurobiology and Neuroimaging into Research on Addiction and PTSDK02DA039229 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BACK, SUDIE E · 2015 to 2019
$779k
Effects of Oxytocin on Alcohol Craving and Intimate Partner AggressionK23AA023845 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI FLANAGAN, JULIANNE CHRISTINA · 2016 to 2019
$774k
NIAAA NIH HHS K23 AA023845NIAAA NIH HHS T32 AA007474NICHD NIH HHS K12 HD055885NIDA NIH HHS K02 DA039229
6 · The paper itself

Abstract

Emerging literature indicates individual and contextual differences impact response to oxytocin (OT). Intimate partner violence (IPV) is one chronic stressor that may moderate OT response. To test the hypothesis that IPV moderates the association between OT and reactivity to a dyadic conflict task, data from a larger randomized controlled study was collected from heterosexual couples (N = 60 individuals; 30 couples) at high risk for IPV due to substance misuse. Partners within each dyad completed a 10-minute dyadic conflict task in the laboratory, and then self-administered a single dose of OT (40 IU) or placebo. Forty-five minutes later, participants completed another 10-minute dyadic conflict task. Stress reactivity was measured before and after the second conflict task using neuroendocrine (i.e., salivary cortisol), physiological (i.e., skin conductance), and subjective responses. Couple conflict behaviors were observed during the conflict tasks and assessed using a validated coding system. Among women, physical IPV modulated skin conductance in those administered OT, and OT interacted with physical and psychological IPV to yield less positive subjective and behavioral responses. No main or moderating effects were found for men. Findings support emerging literature on sex differences in response to OT. Future research is needed to effectively translate OT into therapeutic intervention.

Indexed as

Conflict, PsychologicalSex CharacteristicsAdultFemaleGalvanic Skin ResponseHumansHydrocortisoneInterpersonal RelationsIntimate Partner ViolenceMaleOxytocicsOxytocinRandom AllocationSalivaSexual PartnersSurveys and QuestionnairesHydrocortisoneOxytocicsOxytocinCouplesIntimate partner violenceOxytocinSex differencesSubstance use

Identifiers

PMID30308464
PMCPMC6292734
OpenAlexW2894815037

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.