Evidence map›Paper›PMID 30307960›Full record

ArticlePloS one2018

Cataract surgery and age-related cognitive decline: A 13-year follow-up of the English Longitudinal Study of Ageing.

Asri Maharani, Piers Dawes, James Nazroo, Gindo Tampubolon, Neil Pendleton, SENSE-Cog WP1 group

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

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  16. Associations between Visual Acuity and Cognitive Decline in Older Adulthood: A 9-Year Longitudinal Study.Journal of the International Neuropsychological Society : JINS · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Asri MaharaniDivision of Neuroscience and Experimental Psychology, University of Manchester, Manchester, United Kingdom.ORCID 0000-0002-5931-8692
Piers DawesDivision of Human Communication, Development & Hearing, University of Manchester, Manchester, United Kingdom.ORCID 0000-0003-3180-9884
James NazrooCathie Marsh Institute for Social Research, University of Manchester, Manchester, United Kingdom.
Gindo TampubolonCathie Marsh Institute for Social Research, University of Manchester, Manchester, United Kingdom.
Neil PendletonDivision of Neuroscience and Experimental Psychology, University of Manchester, Manchester, United Kingdom.
SENSE-Cog WP1 group
University of Manchester · GB

Funding

Project-001R01AG017644 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI Andrew Steptoe · 2000 to 2026
$56.2M
NIA NIH HHS R01 AG017644
6 · The paper itself

Abstract

backgroundVisual impairment has been associated with lower cognitive ability among older adults, yet little is known about whether improving visual function with cataract surgery would be associated with slower cognitive decline. This study aimed to assess whether trajectories of cognitive decline differed before and after cataract surgery and compare those trajectories between older adults with cataract surgery and without cataract. METHODS AND

findingsData were drawn from the English Longitudinal Study of Ageing (ELSA) Wave 1 (2002/03) until Wave 7 (2014/15). The study population consisted of 2,068 individuals who underwent cataract surgery between Wave 2 and Wave 6 as the treatment group and 3,636 individuals with no cataract as the control group. We included only respondents who took part in a minimum three waves. Propensity score matching method was used to match the individuals in the treatment group with those in the control group. After we put an "artificial" intervention point for the individuals in the control group at the point that the matched person has cataract surgery, spline method was used to identify differences in cognitive trajectories pre- and post-cataract surgery. In the treatment group, we found that cataract surgery was positively associated with episodic memory scores after controlling for the potential covariates (β = 4.23, p<0.001). Episodic memory scores declined with older age, but the decline in episodic memory scores was slower after cataract surgery (β = -0.05, p<0.001) than before cataract surgery (β = -0.1, p<0.001). Although the episodic memory among respondents in the control group before intervention (β = -0.08, p<0.001) declined slower than those in the intervention group (β = -0.1, p<0.001), the declines in episodic memory scores were similar in both groups after the intervention (control: β = -0.05, p<0.001; intervention: β = -0.05, p<0.001).

conclusionsCataract surgery may have a positive impact on trajectories of cognitive decline in later life. Further research is required to identify the mechanism to explain the association between cataract surgery and cognitive ageing, and whether early intervention towards vision correction results in a reduction in dementia risk.

Indexed as

Cognitive AgingMemory, EpisodicAgedCase-Control StudiesCataract ExtractionCognitive DysfunctionFemaleHumansLongitudinal StudiesMaleMiddle AgedNeuropsychological TestsPropensity ScoreTreatment Outcome

Identifiers

PMID30307960
PMCPMC6181298
OpenAlexW2896894456

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.