ArticlePaediatric and perinatal epidemiology2019
Modifiable life style factors and risk for incident endometriosis.
Article in Paediatric and perinatal epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06795243 (Efficacy of Physical Therapy Treatment in Endometriosis and Its Relationship to Adherence Rates.), which is not on this map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Physical Therapy Treatment in Endometriosis and Its Relationship to Adherence Rates.
Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Racial disparities in uterine fibroids and endometriosis: a systematic review and application of social, structural, and political context.Fertility and sterility · 2023Pooled it
- A systematic review and meta-analysis on alcohol consumption and risk of endometriosis: an update from 2012.Scientific reports · 2022Pooled it
- The Relation between Caffeine Consumption and Endometriosis: An Updated Systematic Review and Meta-Analysis.Nutrients · 2021Pooled it
- Sex-Stratified Genetic Analyses Mapping the Influences of Sedentary Behaviors and Physical Activity on Female Reproductive Health.Research (Washington, D.C.) · 2026Article
- Review
- Non-Invasive Diagnosis of Endometriosis by Questionnaires in Patients Using Contraception.Journal of clinical medicine · 2025Article
- The Impact of Nutrition on Endometriosis Complaints in Patients Using and Not Using Hormone Therapy.Nutrients · 2025Article
- A computational framework for defining and validating reproducible phenotyping algorithms of 313 diseases in the UK Biobank.Scientific reports · 2025Article
- The health-promoting lifestyle and its relationship with the impacts of endometriosis on women's lives in Iran, 2022: a cross-sectional study.BMC women's health · 2025Article
- Analysis of the Biopsychosocial Impacts Associated with Endometriosis to Improve Patient Care.Journal of clinical medicine · 2025Review
- Leveraging epigenetic aberrations in the pathogenesis of endometriosis: from DNA methylation to non-coding RNAs.Frontiers in genetics · 2025Review
- Association between dietary selenium intake and endometriosis risk: a cross-sectional analysis.Frontiers in endocrinology · 2025Article
- Predicting the risk of endometriosis in Chinese infertile women: development and assessment of a predictive nomogram.Frontiers in surgery · 2025Article
- Smoking and endometriosis: A narrative review.Tobacco induced diseases · 2025Review
- Causal relationship between physical activity and common gynecologic conditions: a two-sample Mendelian randomization study.American journal of translational research · 2025Article
- Establishing an electronic patient-reported outcome (ePRO) for patients with endometriosis and chronic pelvic pain: A pilot feasibility study.Journal of clinical and translational science · 2025Article
- Predicting disease recurrence in patients with endometriosis: an observational study.BMC medicine · 2024Observational
- Pathogenesis of Endometriosis and Endometriosis-Associated Cancers.International journal of molecular sciences · 2024Review
- Common Beverage Consumption and Benign Gynecological Conditions.Beverages (Basel, Switzerland) · 2024Article
- Psychometric evaluation of the endometriosis impact questionnaire (EIQ) in an Iranian population.BMC women's health · 2024Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundCaffeine, alcohol, smoking and physical activity are known to alter sex steroid synthesis, which may affect hormone-dependent gynaecologic disease risk, such as endometriosis; however, few studies have assessed life style factors prior to endometriosis diagnosis.
methodsFour hundred and seventy three women, ages 18-44 years, underwent laparoscopy or laparotomy, regardless of clinical indication, at 14 clinic sites, 2007-2009. Women with prior surgically confirmed endometriosis were excluded. Life style factors were assessed prior to surgery. Adjusted risk ratios (RR) of endometriosis by caffeine, alcohol, smoking (serum cotinine), and physical activity were estimated, adjusting for age, marital status, education, race/ethnicity, age at menarche, gravidity, BMI, study site, and other life style factors.
resultsThere were no associations between women with endometriosis and alcohol consumption (RR 0.9, 95% CI 0.7, 1.3), caffeine consumption (RR 1.1, 95% CI 0.8, 1.5), or smoking (serum cotinine <10 vs ≥10 ng/mL; RR 1.0, 95% CI 0.7, 1.6). Similar null findings were found between endometriosis and weekly occurrences of physical activity and total walking, moderate, and vigorous activity; a modest trend was found between total daily sitting time and increased endometriosis risk.
conclusionsThis study, which is unique in its capture of life style exposures prior to incident endometriosis diagnosis, largely found no association between alcohol, caffeine, smoking, and physical activity and risk of endometriosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.