Evidence map›Paper›PMID 30307609›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2019

Effect of locally tailored clinical guidelines on intrapartum management of severe hypertensive disorders at Zanzibar's tertiary hospital (the PartoMa study).

Nanna Maaløe, Camilla B Andersen, Natasha Housseine, Tarek Meguid, Ib C Bygbjerg, Jos van Roosmalen

Registry-linked trialAbstract read
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02318420 (The PartoMa Project for Saving Lives at Birth - An Intervention Based Study to Strengthen the Quality of Monitoring, Action and Triage During Labour at an East African Referral Hospital), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02318420 nacompletednot on this map

The PartoMa Project for Saving Lives at Birth - An Intervention Based Study to Strengthen the Quality of Monitoring, Action and Triage During Labour at an East African Referral Hospital

TypeinterventionalSponsorIb Christian BygbjergRan2014 to 2018Enrolled3,087ConditionsObstetric Labor Complications, Stillbirth, Maternal DeathArmsThe PartoMa intervention
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nanna MaaløeGlobal Health Section, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Camilla B AndersenGlobal Health Section, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Natasha HousseineMnazi Mmoja Hospital, Zanzibar City, Tanzania.
Tarek MeguidMnazi Mmoja Hospital, Zanzibar City, Tanzania.
Ib C BygbjergGlobal Health Section, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Jos van RoosmalenAthena Institute, VU University of Amsterdam, Amsterdam, Netherlands.

Funding

Augustinus FoundationLaerdal FoundationLundbeck FoundationUniversity of Copenhagen
6 · The paper itself

Abstract

objectiveTo estimate the effect of locally tailored clinical guidelines on intrapartum care and perinatal outcomes among women with severe hypertensive disorders in pregnancy (sHDP).

methodsA pre-post study at Zanzibar's low-resource Mnazi Mmoja Hospital was conducted. All labouring women with sHDP were included at baseline (October 2014 to January 2015) and at 9-12 months after implementation of the ongoing intervention (October 2015 to January 2016). Background characteristics, clinical practice, and delivery outcomes were assessed by criterion-based case file reviews.

resultsOverall, 188 of 2761 (6.8%) women had sHDP at baseline, and 196 of 2398 (8.2%) did so during the intervention months. The median time between last blood pressure recording and delivery decreased during the intervention compared with baseline (P=0.015). Among women with severe hypertension, antihypertensive treatment increased during the intervention compared with baseline (relative risk [RR] 1.37, 95% confidence interval [CI] 1.14-1.66). Among the neonates delivered (birthweight ≥1000 g), stillbirths decreased (RR 0.56, 95% CI 0.35-0.90) and Apgar scores of seven or more increased during the intervention compared with baseline (RR 1.17, 95% CI 1.03-1.33).

conclusionAlthough health system strengthening remains crucial, locally tailored clinical guidelines seemed to help work-overloaded birth attendants at a low-resource hospital to improve care for women with sHDP. CLINICALTRIALS.ORG: NCT02318420.

Indexed as

Practice Guidelines as TopicAnticonvulsantsAntihypertensive AgentsApgar ScoreDelivery, ObstetricFemaleHumansHydralazineHypertension, Pregnancy-InducedInfant, NewbornMidwiferyPovertyPregnancyPregnancy OutcomeQuality ImprovementRetrospective StudiesAnticonvulsantsAntihypertensive AgentsHydralazineBirth asphyxiaGuidelinesLaborPartoMaPre-eclampsiaSevere hypertensive disordersStillbirthTanzania

Identifiers

PMID30307609
PMCPMC7379925

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.