ReviewClinical oral implants research2018
How do peri-implant biologic parameters correspond with implant survival and peri-implantitis? A critical review.
Review in Clinical oral implants research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 4 syntheses or guidelines pooled it, 89 citations in OpenAlex.
- Impact and efficacy of systemic antibiotics for peri-implant diseases treatment: A systematic review and meta-analysis on clinical and microbiological outcomes.Periodontology 2000 · 2025Pooled it
- The role of probiotic therapy on clinical parameters and human immune response in peri-implant diseases: a systematic review and meta-analysis of randomized clinical studies.Frontiers in immunology · 2024Pooled it
- Clinical efficacy of adjunctive methods for the non-surgical treatment of peri-implantitis: a systematic review and meta-analysis.BMC oral health · 2023Pooled it
- Efficacy of growth factors for the treatment of peri-implant diseases: a systematic review and meta-analysis.Clinical oral investigations · 2020Pooled it
- Ozonized Hydrogel and Chlorhexidine Gel for Peri-Implant Mucositis: A 24-Month Randomized Controlled Trial.Oral diseases · 2026Trial
- Evolution in the Peri-Implant Oral Microbiome and Their Relationship to Long-Term Marginal Bone Loss: A Randomized Clinical Study.Clinical oral implants research · 2025Trial
- The effect of choline-stabilized orthosilicic acid in patients with peri-implantitis: an exploratory randomized, double-blind, placebo controlled study.BMC oral health · 2021Trial
- A clinical and radiographic study of implants placed in autogenous bone grafts covered by either a platelet-rich fibrin membrane or deproteinised bovine bone mineral and a collagen membrane: a pilot randomised controlled clinical trial with a 2-year follow-up.International journal of implant dentistry · 2021Trial
- Clinical performance of a conometric retention system for single implant restorations: 1-year analysis of a prospective multicenter study.International journal of implant dentistry · 2026Article
- Does using concave abutments improve 24-month outcomes of single posterior implants?Evidence-based dentistry · 2026Article
- Timing and extent of Peri-Implant bone loss for dental implant removal: A retrospective Cross-Sectional analysis.Clinical oral investigations · 2026Article
- Clinical Trends in the Prevention of Peri-Implantitis: Spanish Society of Periodontology (SEPA) Foundation Survey Using the Delphi Method.Clinical oral implants research · 2025Article
- Label-free distinction of implant infection-associated bacterial biofilms by Mueller matrix polarimetry.Journal of biomedical optics · 2025Article
- A 10-Year Follow-Up of Reconstructive Treatment of Peri-Implantitis Using Mineralized Dehydrated Allograft and Resorbable Membrane: A Retrospective Case Series.Clinical oral implants research · 2025Article
- Prevalence of Peri-Implant Diseases in a Private Practice and Potential Risk Indicators.Oral health & preventive dentistry · 2025Article
- Comprehensive Analysis of Immune Infiltration and Key Genes in Peri-Implantitis Using Bioinformatics and Molecular Biology Approaches.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Nanostructured Implant-Tissue Interface Assessment Using a Three-Dimensional Gingival Tissue Equivalent.ACS omega · 2024Article
- Article
- Long-Term Effect of Guided Implant Surgery on Clinical Outcomes and Peri-Implantitis of Maxillary Implants-An Observational Cohort Study.Journal of clinical medicine · 2023Article
- Incidence of Peri-Implantitis, Technical and Biological Complications of Single Implants Placed with Flap or Flapless Surgery-A 10-12-Year Case-Series.Journal of clinical medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this critical review was to evaluate whether commonly used biologic diagnostic parameters correspond to implant survival and peri-implantitis prevalence. MATERIALS AND
methodsPublications from 2011 to 2017 were selected by an electronic search using the Pubmed database of the US National Library of Medicine. Prospective and retrospective studies with a mean follow-up time of at least 5 years and reporting prevalence of peri-implantitis as well as mean bone loss and standard deviation were selected. The correlation between reported prevalence of peri-implantitis and reported implant survival, mean follow-up time, mean bone loss, mean probing depth, and mean bleeding on probing was calculated. Mean bone loss and standard deviation were used for estimation of proportion of implants with bone loss exceeding 1, 2, and 3 mm.
resultsFull-text analysis was performed for 255 papers from 4,173 available ones, and 41 met all the inclusion criteria. The overall mean weighted survival rate was 96.9% (89.9%-100%) and the reported prevalence of peri-implantitis ranged between 0% and 39.7%, based on 15 different case definitions. The overall weighted bone loss was 1.1 mm based on 8,182 implants and an average mean loading time ranging from 5 to 20 years. No correlation was found between mean bone loss and the reported prevalence of peri-implantitis. The estimated prevalence of implants with bone loss above 2 mm was 23%. The overall weighted mean probing depth was 3.3 mm, and mean weighted bleeding was 52.2%. Only a weak correlation was found between survival and function time (r = -0.49). There was no relation between the probing depth or bleeding and the mean bone loss, mean follow-up time, and reported prevalence of peri-implantitis.
conclusionBiologic parameters mean probing depth and mean bleeding on probing do not correlate with mean bone loss and this irrespective of follow-up. Case definition for peri-implantitis varied significantly between studies indicating that an unambiguous definition based on a specified threshold for bone loss is not agreed upon in the literature.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.