Evidence map›Paper›PMID 30306534›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019

Hearing loss and quality of life in survivors of paediatric CNS tumours and other cancers.

Annette Weiss, Grit Sommer, Christina Schindera, Laura Wengenroth, Axel Karow, Manuel Diezi, Gisela Michel, Claudia E Kuehni, Swiss Paediatric Oncology Group (SPOG)

2 registry-linked trialsOpen access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03297034 recruitingnot on this map

Swiss Childhood Cancer Survivor Study (SCCSS)

Typeobservational_patient_registrySponsorUniversity of BernRan2007 to 2050Enrolled4,136ConditionsChildhood Cancer
NCT06036407 nacompletednot on this mapstarted 2022, after this paper: background citation

Improving Access to Screening for Hearing Loss After Childhood Cancer - a Novel Community-based Approach

TypeinterventionalSponsorUniversity of BernRan2022 to 2024Enrolled476ConditionsChildhood Cancer, Hearing LossArmsHearing test
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Remote Field Application of Digital Technology for Hearing Assessments in a Cohort of Pediatric Germ Cell Tumor Survivors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  6. Review
  7. Long-term auditory follow-up in the management of pediatric platinum-induced ototoxicity.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Annette WeissSwiss Childhood Cancer Registry, Institute of Social and Preventive Medicine, University of Bern, Mittelstrasse 43, 3012, Bern, Switzerland.ORCID http://orcid.org/0000-0001-8295-3574
Grit SommerSwiss Childhood Cancer Registry, Institute of Social and Preventive Medicine, University of Bern, Mittelstrasse 43, 3012, Bern, Switzerland.
Christina SchinderaSwiss Childhood Cancer Registry, Institute of Social and Preventive Medicine, University of Bern, Mittelstrasse 43, 3012, Bern, Switzerland.
Laura WengenrothInstitute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital of Munich (LMU), 80336, Munich, Germany.
Axel KarowDivision of Pediatric Hematology/Oncology, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Freiburgerstrasse 15, 3010, Bern, Switzerland.
Manuel DieziPaediatric Haemato-Oncology Unit, Department of Paediatrics, University Hospital Lausanne (CHUV), Rue du Bugnon 46, 1011, Lausanne, Switzerland.
Gisela MichelDepartment of Health Sciences and Health Policy, University of Lucerne, Frohburgstrasse 3, 6002, Lucerne, Switzerland.ORCID http://orcid.org/0000-0002-9589-0928
Claudia E KuehniSwiss Childhood Cancer Registry, Institute of Social and Preventive Medicine, University of Bern, Mittelstrasse 43, 3012, Bern, Switzerland. claudia.kuehni@ispm.unibe.ch.ORCID http://orcid.org/0000-0001-8957-2002
Swiss Paediatric Oncology Group (SPOG)
University of Bern · CHUniversity of Lucerne · CHLMU Klinikum · DEUniversity Hospital of Lausanne · CH

Funding

European Union's Seventh Framework Programme for research, technological development and demonstration 602030Swiss Cancer League 3412-02-2014Swiss Cancer League 3886-02-2016
6 · The paper itself

Abstract

purposeHearing loss, a complication of cancer treatment, may reduce health-related quality of life (HRQoL), especially in childhood cancer survivors of central nervous system (CNS) tumours who often have multiple late effects. We examined the effect of hearing loss on HRQoL in young survivors of CNS and other childhood cancers.

methodsWithin the Swiss Childhood Cancer Survivor Study, we sent questionnaires about hearing loss and HRQoL (KIDSCREEN-27) to parents of survivors aged 8-15 years. We stratified the effect of hearing loss on HRQoL by cancer diagnosis, using multivariable logistic regression and adjusting for sociodemographic and clinical factors.

resultsHearing loss was associated with impaired physical well-being [unadjusted estimated differences - 4.6 (CI - 9.2, - 0.1); adjusted - 4.0 (CI - 7.6, - 0.3)] and peers and social support [unadjusted - 6.7 (CI - 13.0, - 0.3); adjusted - 5.0 (CI - 10.5, 0.9)] scores in survivors of CNS tumours (n = 123), but not in children diagnosed with other cancers (all p-values > 0.20, n = 577).

conclusionClinicians should be alert to signs of reduced physical well-being and impaired relationships with peers. Especially survivors of CNS tumours may benefit most from strict audiological monitoring and timely intervention to mitigate secondary consequences of hearing loss on HRQoL.

Indexed as

Cancer SurvivorsCentral Nervous System NeoplasmsChild, PreschoolFemaleHearing LossHumansMaleQuality of LifeSurveys and QuestionnairesCancer treatmentChildhood cancerLate effectsOtotoxicitySwiss Childhood Cancer RegistrySwiss Childhood Cancer Survivor Study

Identifiers

PMID30306534
OpenAlexW2896226360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.