Evidence map›Paper›PMID 30306425›Full record

ArticleEuropean journal of epidemiology2019

Hearing loss, cognitive ability, and dementia in men age 19-78 years.

Merete Osler, Gunhild Tidemann Christensen, Erik Lykke Mortensen, Kaare Christensen, Ellen Garde, Maarten Pieter Rozing

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
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  14. Hearing Loss and Alzheimer Disease.Current topics in behavioral neurosciences · 2025
    Review
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  18. No Influence of Age-Related Hearing Loss on Brain Amyloid-β.Journal of Alzheimer's disease : JAD · 2022
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Merete OslerCenter for Clinical Research and Disease Prevention, Bispebjerg and Frederiksberg Hospitals, Nordre Fasanvej 57, 2000, Frederiksberg, Copenhagen, Denmark. Merete.osler@regionh.dk.ORCID http://orcid.org/0000-0002-6921-220X
Gunhild Tidemann ChristensenCenter for Clinical Research and Disease Prevention, Bispebjerg and Frederiksberg Hospitals, Nordre Fasanvej 57, 2000, Frederiksberg, Copenhagen, Denmark.
Erik Lykke MortensenDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark.
Kaare ChristensenDanish Aging Research Center, Institute of Public Health, University of Southern Denmark, Odense, Denmark.
Ellen GardeDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark.
Maarten Pieter RozingDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DKUniversity of Southern Denmark · DK

Funding

Jascha Fonden NASundhed og Sygdom, Det Frie Forskningsråd 09-063599Velux Fonden 31205
6 · The paper itself

Abstract

Hearing loss in later life has been associated with risk of dementia. The impact of risk factors for dementia may change during life, and it is unknown whether hearing loss early in midlife represents a risk factor for dementia. We examined whether hearing loss diagnosed in midlife was associated with an increased risk of dementia. A cohort comprising 942,567 Danish men enrolled in the mandatory conscription board examination was followed from conscription (age 19). Cognitive ability was measured at conscription, while hearing loss was ascertained either by physicians diagnosis at conscription or by the Danish National Patient Registry from 1977 to 2016 (ICD-8:388; 389; ICD-10:H90; H91). Differences in cognitive ability in relation to hearing loss at conscription were calculated using t test, while the risk of dementia associated with hearing loss was estimated using Cox regression with adjustment for cognitive ability, education, depression, diabetes, hypertension, and cerebrovascular disease. Men with hearing loss at conscription had about 2 points (corresponding to 0.20 SD) lower mean cognitive score than those without hearing loss. During follow-up, 59,834 men had a hearing loss diagnosis, while 9114 were diagnosed with dementia. Midlife hearing loss was associated with an increased rate of dementia diagnosed before age 60 (adjusted Hazard Ratio (HR) = 1.90 [95% CI 1.59-2.76]) or at a later age (adjusted HR = 1.15 [95% CI 1.06-1.25]). Our study supports the evidence that early identification and correction of hearing loss holds promise for prevention of dementia later in life.

Indexed as

CognitionAdultAgedCerebrovascular DisordersCohort StudiesDementiaDenmarkDepressionDiabetes MellitusHearing LossHumansHypertensionMaleMiddle AgedProportional Hazards ModelsRisk AssessmentCognitive abilityCohort studyDementiaHearing loss

Identifiers

PMID30306425
OpenAlexW2896458777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.