ReviewCurrent psychiatry reports2018
Estrogens, Aging, and Working Memory.
Review in Current psychiatry reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Evidence for a robust, estradiol-associated sex difference in narrative-writing fluency.Neuropsychology · 2021Pooled it
- Menstrual cycle phase affects alcohol impairment of working memory.Alcohol, clinical & experimental research · 2025Trial
- Age-Related Changes in Density, Arborization, and NMDA Receptor Expression in Somatostatin Interneurons of the Mouse mPFC.The Journal of comparative neurology · 2026Article
- Article
- Pubertal Hormones and the Early Adolescent Female Brain: A Multimodality Brain MRI Study.Human brain mapping · 2026Article
- Chronological age is differentially associated with cognitive performance according to climacteric stage: evidence from a Bayesian multivariate analysis in Chilean women.Frontiers in psychology · 2026Article
- Observational
- N-back task revisited: Comparing the neural correlates of updating and interference control.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Estradiol and the Catechol-o-methyltransferase Gene Interact to Predict Working Memory Performance: A Replication and Extension.Journal of cognitive neuroscience · 2023Article
- Deciphering the Influence of Estradiol and Estrogen Receptors on Cognitive Function: A Bibliometric Analysis and Emerging Research Trends.Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- Late-onset Cognitive Impairment and Modifiable Risk Factors in Adult Childhood Cancer Survivors.JAMA network open · 2023Article
- Article
- Centering the Needs of Transgender, Nonbinary, and Gender-Diverse Populations in Neuroendocrine Models of Gender-Affirming Hormone Therapy.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Review
- Novel molecular mechanisms in Alzheimer's disease: The potential role of DEK in disease pathogenesis.Frontiers in aging neuroscience · 2022Review
- Sex Hormones, Sleep, and Memory: Interrelationships Across the Adult Female Lifespan.Frontiers in aging neuroscience · 2022Review
- Estrogen, Cognitive Performance, and Functional Imaging Studies: What Are We Missing About Neuroprotection?Frontiers in cellular neuroscience · 2022Review
- Age, Sex, and Inhibitory Control: Identifying a Specific Impairment in Memorial, But Not Perceptual, Inhibition in Older Women.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021Article
- Estradiol selectively regulates metabolic substrates across memory systems in models of menopause.Climacteric : the journal of the International Menopause Society · 2021Article
- On the role of sex steroids in biological functions by classical and non-classical pathways. An update.Frontiers in neuroendocrinology · 2021Review
- Brain functional changes in perimenopausal women: an amplitude of low-frequency fluctuation study.Menopause (New York, N.Y.) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewWorking memory (WM) is a key process that is integral to many complex cognitive tasks, and it declines significantly with advancing age. This review will survey recent evidence supporting the idea that the functioning of the WM system in women is modulated by circulating estrogens. RECENT
findingsIn postmenopausal women, increased estrogen concentrations may be associated with improved WM function, which is evident on WM tasks that have a high cognitive load or significant manipulation demands. Experimental studies in rhesus monkeys and human neuroimaging studies support a prefrontal locus for these effects. Defining the basic neurochemical or cellular mechanisms that underlie the ability of estrogens to regulate WM is a topic of current research in both human and animal investigations. An emerging body of work suggests that frontal executive elements of the WM system are influenced by the circulating estrogen concentrations currently available to the CNS and that the effects are region-specific within the frontal cortex. These findings have implications for women's brain health and cognitive aging.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.