Evidence map›Paper›PMID 30306335›Full record

ArticleClinical oral investigations2019

Effect of NaF, AmF, KF gels and NaF toothpaste combined with a saliva substitute on dentin lesions in vitro.

Carolin Walther, Manana Kreibohm, Sebastian Paris, Hendrik Meyer-Lueckel, Peter Tschoppe, Richard Johannes Wierichs

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical oral investigations, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Carolin WaltherDepartment of Operative Dentistry, Periodontology and Preventive Dentistry, University Hospital RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Germany.
Manana KreibohmDepartment of Operative Dentistry, Periodontology and Preventive Dentistry, University Hospital RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Germany.
Sebastian ParisDepartment of Operative Dentistry and Periodontology, University School of Dental Medicine, CharitéCentrum 3, Charité - Universitätsmedizin Berlin, Aßmannshauser Straße 4-6, 14197, Berlin, Germany.
Hendrik Meyer-LueckelDepartment of Operative Dentistry, Periodontology and Preventive Dentistry, University Hospital RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Germany.
Peter TschoppeDepartment of Operative Dentistry, Periodontology and Preventive Dentistry, University Hospital RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Germany.
Richard Johannes WierichsDepartment of Operative Dentistry, Periodontology and Preventive Dentistry, University Hospital RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Germany. rwierichs@ukaachen.de.ORCID http://orcid.org/0000-0002-4239-199X
RWTH Aachen University · DEUniversity of Bern · CHCharité - Universitätsmedizin Berlin · DEUniversitätsklinikum Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the present in vitro study was to evaluate the remineralizing effects of NaF, AmF, KF gels and NaF toothpaste in combination with a potentially demineralizing saliva substitute (Glandosane; pH = 5.1) being widely used in Germany.

methodsIn each of 120 dentin specimens, three artificial lesions were created. One lesion was covered for analysis of pre-demineralization (ΔZ

resultsMean (95%CI) ΔZ

conclusionUnder the in vitro conditions chosen, all fluoride agents could significantly hamper the adverse effects of a demineralizing saliva substitute. CLINICAL SIGNIFICANCE: In combination with a demineralizing saliva substitute, slight mineral gain was only observed for neutral NaF-gel

Indexed as

Tooth RemineralizationAnimalsCariostatic AgentsCattleDentinFluoridesGelsGermanySalivaSodium FluorideToothpastesCariostatic AgentsFluoridesGelsSodium FluorideToothpastesDentinFluoridesHyposalivationNon-cavitated caries lesionspH cyclingRemineralizationSaliva

Identifiers

PMID30306335
OpenAlexW2896344382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.