Evidence map›Paper›PMID 30306286›Full record

ArticleLung2019

Characterization and Triggers of Dyspnea in Patients with Chronic Obstructive Pulmonary Disease or Chronic Heart Failure: Effects of Weather and Environment.

Ayham Daher, Michael Matthes, András Keszei, Vincent Brandenburg, Tobias Müller, Christian Cornelissen, Michael Dreher

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Lung, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ayham DaherDepartment of Pneumology and Intensive Care Medicine, University Hospital Aachen, Aachen, Germany.
Michael MatthesDepartment of Pneumology and Intensive Care Medicine, University Hospital Aachen, Aachen, Germany.
András KeszeiDepartment of Medical Informatics, University Hospital Aachen, Aachen, Germany.
Vincent BrandenburgDepartment of Cardiology, Angiology and Intensive Care Medicine, University Hospital Aachen, Aachen, Germany.
Tobias MüllerDepartment of Pneumology and Intensive Care Medicine, University Hospital Aachen, Aachen, Germany.
Christian CornelissenDepartment of Pneumology and Intensive Care Medicine, University Hospital Aachen, Aachen, Germany.
Michael DreherDepartment of Pneumology and Intensive Care Medicine, University Hospital Aachen, Aachen, Germany. mdreher@ukaachen.de.ORCID 0000-0002-3452-5329
Universitätsklinikum Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesDyspnea is one of the most disturbing symptoms for patients with chronic obstructive pulmonary disease (COPD) or heart failure (HF). This study investigated dyspnea triggers and factors associated with worsening dyspnea in patients with COPD or HF.

methodsCOPD support group members and HF patients with reduced ejection fraction (HFrEF) and no airway obstruction answered a questionnaire describing different weather conditions (rising/falling air pressure, sunny, foggy, rainy, windy, snowy, hazy, high ozone levels, and airborne pollen) and environmental circumstances (cooking, grilling, perfumes, cigarette smoke, gasoline odor, and flower scents) and were asked to estimate the occurrence and severity of dyspnea under these conditions using predefined scales.

results230 patients with COPD and 90 with HFrEF (left ventricular ejection fraction 34 ± 10%, Tiffeneau index > 70%) were analyzed. COPD patients reported dyspnea more often than HF patients in almost all weather and environmental conditions (p = 0.004 to p < 0.001), with the exception of outdoor floral scents and cigarette smoke. Severe to very severe dyspnea was reported more in COPD versus HF in all weather and environmental conditions except sunny weather (p = 0.01 to p < 0.001). COPD was associated with more severe dyspnea than HF in all conditions (all p < 0.001).

conclusionsDyspnea was triggered by a variety of weather and other environmental triggers in patients with COPD and occurred more often than in HF patients under the same conditions. Foggy weather and exposure to perfumes were associated with severe dyspnea in the majority of COPD patients, but only a minority of HF patients.

Indexed as

WeatherAgedAged, 80 and overChronic DiseaseDyspneaEnvironmental ExposureEnvironmental PollutantsFemaleHeart FailureHumansLungMaleMiddle AgedPerfumePulmonary Disease, Chronic ObstructiveRisk FactorsEnvironmental PollutantsPerfumeSmokeChronic obstructive pulmonary diseaseDyspneaEnvironmentHeart failureWeather

Identifiers

PMID30306286
OpenAlexW2895902873

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.