ArticleScience advances2018
Genomic and functional evidence reveals molecular insights into the origin of echolocation in whales.
Article in Science advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 33 citations in OpenAlex.
- Decoding the functional adaptation of animal echolocation: a global macroevolutionary analysis.Science China. Life sciences · 2026Article
- The genetic foundations of convergent traits.Nature reviews. Genetics · 2026Review
- Molecular Evidence for the Parallel Evolution of Anosmia in Multiple Odontoceti (Toothed Whales) Clades.Genes · 2026Article
- Evidence for echolocation in Asian shrew moles.National science review · 2026Article
- Emerging technologies for advancing molecular and cellular research in bats.Zoological research · 2026Review
- Structural Mechanism of Prestin-Membrane Mechanotransduction.bioRxiv : the preprint server for biology · 2025Article
- Chloride binding does not influence prestin motor speed at very high frequencies in the mouse outer hair cell.Structure (London, England : 1993) · 2025Article
- Evolutionary sparse learning reveals the shared genetic basis of convergent traits.Nature communications · 2025Article
- Molecular evolution of toothed whale genes reveals adaptations to echolocating in different environments.BMC genomics · 2024Article
- WGCCRR: a web-based tool for genome-wide screening of convergent indels and substitutions of amino acids.Bioinformatics advances · 2024Article
- Evolution of high-molecular-mass hyaluronic acid is associated with subterranean lifestyle.Nature communications · 2023Article
- Untargeted metabolomics of the cochleae from two laryngeally echolocating bats.Frontiers in molecular biosciences · 2023Article
- Prestin-Mediated Frequency Selectivity Does not Cover Ultrahigh Frequencies in Mice.Neuroscience bulletin · 2022Article
- Molecular convergence and transgenic evidence suggest a single origin of laryngeal echolocation in bats.iScience · 2022Article
- Article
- Comparative genomics provides insights into the aquatic adaptations of mammals.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Assessing evidence for adaptive evolution in two hearing-related genes important for high-frequency hearing in echolocating mammals.G3 (Bethesda, Md.) · 2021Article
- Recurrent sequence evolution after independent gene duplication.BMC evolutionary biology · 2020Article
- Evolutionary Basis of High-Frequency Hearing in the Cochleae of Echolocators Revealed by Comparative Genomics.Genome biology and evolution · 2020Article
- Genomic Insights into the Adaptive Convergent Evolution.Current genomics · 2019Review
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5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Echolocation allows toothed whales to adapt to underwater habitats where vision is ineffective. Because echolocation requires the ability to detect exceptional high-frequency sounds, fossils related to the auditory system can help to pinpoint the origin of echolocation in whales. However, because of conflicting interpretations of archaeocete fossils, when and how whales evolved the high-frequency hearing correlated with echolocation remain unclear. We address these questions at the molecular level by systematically investigating the convergent evolution of 7206 orthologs across 16 mammals and find that convergent genes between the last common ancestor of all whales (LCAW) and echolocating bats are not significantly enriched in functional categories related to hearing, and that convergence in hearing-related proteins between them is not stronger than that between nonecholocating mammalian lineages and echolocating bats. However, these results contrast with those of parallel analyses between the LCA of toothed whales (LCATW) and echolocating bats. Furthermore, we reconstruct the ancestral genes for the hearing protein
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