ReviewBiotechnology for biofuels2018
Microalgae for the production of lipid and carotenoids: a review with focus on stress regulation and adaptation.
Review in Biotechnology for biofuels, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.
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Who cites it
99 citing papers in PubMed.
- Triacylglycerol synthesis in microalgae under abiotic stress: an updated integrative review.Plant & cell physiology · 2026Review
- Decoupled accumulation of chlorophylls and total carotenoids between floral and vegetative organs in Dendrobium.BMC plant biology · 2026Article
- Response of aBiology · 2026Article
- Horizontal gene transfer and diploidy illuminate evolution and stress adaptation in oleaginous Scenedesmaceae (Chlorophyta).Nature communications · 2026Article
- Boosting biomass and superoxide dismutase yield in Tetraselmis chuii via two-stage cultivation and adaptive laboratory evolution.Bioprocess and biosystems engineering · 2026Article
- Harnessing microalgae for bioproducts: innovations in synthetic biology.World journal of microbiology & biotechnology · 2025Review
- Optimisation of physicochemical factors for enhanced astaxanthin accumulation in newly isolated freshwater green microalgae Desmodesmus sp. PLM2: insights from current analytical techniques.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Sustainable Nutrient Recovery from Wastewater Mixture to Optimize Microalgal Lipid Production: A Vision of Zero Water Footprint.Bioengineering (Basel, Switzerland) · 2025Article
- Tapping the microalgal potential: genetic precision and stress-induction for enhanced astaxanthin and biofuel production.Biotechnology for biofuels and bioproducts · 2025Review
- Integrated transcriptomics and metabolomics analysis reveal the regulatory mechanisms underlying the combined effects of heat and glucose starvation on carotenoid biosynthesis in Rhodotorula glutinis YM25079.Biotechnology for biofuels and bioproducts · 2025Article
- Moderate levels of dissolved iron stimulate cellular growth and increase lipid storage in Symbiodinium sp.Journal of phycology · 2025Article
- Exploration of a cultivation strategy to improve eicosapentaenoic acid (EPA) production and growth of a Korean strain of Nannochloropsis oceanica cultivated under different light sources.Biotechnology for biofuels and bioproducts · 2025Article
- Egg Quality and Laying Performance of Rhode Island Red Hens Fed with Black Soldier Fly Larvae and Microalgae Meal as an Alternative Diet.Animals : an open access journal from MDPI · 2025Article
- Elevated accumulation of lutein and zeaxanthin in a novel high-biomass yielding strain Dunaliella sp. ZP-1 obtained through EMS mutagenesis.Biotechnology for biofuels and bioproducts · 2025Article
- Amino Acid and Carotenoid Profiles ofBioengineering (Basel, Switzerland) · 2025Article
- Enhancing Biomass and Lipid Production inLife (Basel, Switzerland) · 2025Article
- Regulation of nucleus-encoded trans-acting factors allows orthogonal fine-tuning of multiple transgenes in the chloroplast of Chlamydomonas reinhardtii.Plant biotechnology journal · 2025Article
- Chromosome-level genomes of two Bracteacoccaceae highlight adaptations to biocrusts.Nature communications · 2025Article
- Microalgae biotechnology and its role in sustainable and healthy food design.Frontiers in bioengineering and biotechnology · 2025Review
- Wild or Reared?Marine drugs · 2025Article
39 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microalgae have drawn great attention as promising sustainable source of lipids and carotenoids. Their lipid and carotenoids accumulation machinery can be trigged by the stress conditions such as nutrient limitation or exposure to the damaging physical factors. However, stressful conditions often adversely affect microalgal growth and cause oxidative damage to the cells, which can eventually reduce the yield of the desired products. To overcome these limitations, two-stage cultivation strategies and supplementation of growth-promoting agents have traditionally been utilized, but developing new highly adapted strains is theoretically the simplest strategy. In addition to genetic engineering, adaptive laboratory evolution (ALE) is frequently used to develop beneficial phenotypes in industrial microorganisms during long-term selection under specific stress conditions. In recent years, many studies have gradually introduced ALE as a powerful tool to improve the biological properties of microalgae, especially for improving the production of lipid and carotenoids. In this review, strategies for the manipulation of stress in microalgal lipids and carotenoids production are summarized and discussed. Furthermore, this review summarizes the overall state of ALE technology, including available selection pressures, methods, and their applications in microalgae for the improved production of lipids and carotenoids.
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