Evidence map›Paper›PMID 30305655›Full record

ArticleScientific reports2018

Jack J Miller, James T Grist, Sébastien Serres, James R Larkin, Angus Z Lau, Kevin Ray, Katherine R Fisher, Esben Hansen, Rasmus Stilling Tougaard, Per Mose Nielsen and 5 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 68 citations in OpenAlex.

  1. HyperpolarizedResearch square · 2026
    Article
  2. Article
  3. Clinical Translation of HyperpolarizedAJNR. American journal of neuroradiology · 2025
    Review
  4. Tracking Hyperpolarized [1-NMR in biomedicine · 2025
    Article
  5. Review
  6. HyperpolarizedNMR in biomedicine · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Current methods for hyperpolarized [1-Magnetic resonance in medicine · 2024
    Review
  12. Investigating the origin of theNMR in biomedicine · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. DynamicMagnetic resonance in medicine · 2022
    Article
  18. Hyperpolarization ofRSC advances · 2022
    Article
  19. Review
  20. Probing Cerebral Metabolism with HyperpolarizedACS chemical neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 4 countries.

Jack J MillerDepartment of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, UK. Jack.Miller@physics.org.ORCID http://orcid.org/0000-0002-6258-1299
James T GristDepartment of Radiology, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-7223-4031
Sébastien SerresCancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
James R LarkinCancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-4169-8447
Angus Z LauPhysical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada.
Kevin RayCancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
Katherine R FisherDepartment of Chemistry, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-2716-561X
Esben HansenMR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Rasmus Stilling TougaardMR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Per Mose NielsenMR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Jakob LindhardtMR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Christoffer LaustsenMR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID http://orcid.org/0000-0002-0317-2911
Ferdia A GallagherDepartment of Radiology, University of Cambridge, Cambridge, UK.
Damian J TylerDepartment of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, UK.
Nicola SibsonCancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
Aarhus University · DKCancer Research UK · GBUniversity of Cambridge · GBClarendon College · USJohn Radcliffe Hospital · GBSunnybrook Health Science Centre · CAUniversity of Nottingham · GBUniversity of Oxford · GB

Funding

METALLOTHIONEIN AND CYTOTOXIC DRUG RESISTANCEK08CA001490 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BAHNSON, ROBERT R · 1990 to 1994
–
British Heart Foundation FS/10/002/28078British Heart Foundation FS/14/17/3063British Heart Foundation FS/14/17/30634British Heart Foundation RG/11/9/28921Cancer Research UK 16628Cancer Research UK 16945Cancer Research UK C5255/A12678Cancer Research UK C5255/A16466Medical Research Council G0601490Medical Research Council MC-ST-U13080Medical Research Council MR/K501256/1
6 · The paper itself

Abstract

Hyperpolarised MRI with Dynamic Nuclear Polarisation overcomes the fundamental thermodynamic limitations of conventional magnetic resonance, and is translating to human studies with several early-phase clinical trials in progress including early reports that demonstrate the utility of the technique to observe lactate production in human brain cancer patients. Owing to the fundamental coupling of metabolism and tissue function, metabolic neuroimaging with hyperpolarised [1-

Indexed as

Magnetic Resonance ImagingAnimalsBiological TransportBlood-Brain BarrierBrain NeoplasmsCarbon IsotopesCell Line, TumorFemaleHumansKineticsMannitolPyruvic AcidRatsSwineCarbon-13Carbon IsotopesMannitolPyruvic Acid

Identifiers

PMID30305655
PMCPMC6180068
OpenAlexW2895021881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.