Evidence map›Paper›PMID 30305414›Full record

ReviewThe oncologist2019

Magnetic Resonance Imaging-Based Screening for Asymptomatic Brain Tumors: A Review.

Alfred I Neugut, Paul Sackstein, Grace C Hillyer, Judith S Jacobson, Jeffrey Bruce, Andrew B Lassman, Philip A Stieg

Open access · hybridAbstract readReview
In one paragraph

Review in The oncologist, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Brain imaging with portable low-field MRI.Nature reviews bioengineering · 2023
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Brain metastases: the role of clinical imaging.The British journal of radiology · 2022
    Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alfred I NeugutDepartment of Medicine, Columbia University, New York New York, USA ain1@columbia.edu.
Paul SacksteinDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York New York, USA.
Grace C HillyerDepartment of Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Columbia University, New York New York, USA.
Judith S JacobsonDepartment of Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Columbia University, New York New York, USA.
Jeffrey BruceDepartment of Neurological Surgery, Columbia University, New York New York, USA.
Andrew B LassmanDepartment of Neurology, Columbia University, New York New York, USA.
Philip A StiegDepartment of Neurological Surgery, Weill-Cornell Medical College, New York New York, USA.
Columbia University · USNeurological Surgery · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain tumors comprise 2% of all cancers but are disproportionately responsible for cancer-related deaths. The 5-year survival rate of glioblastoma, the most common form of malignant brain tumor, is only 4.7%, and the overall 5-year survival rate for any brain tumor is 34.4%. In light of the generally poor clinical outcomes associated with these malignancies, there has been interest in the concept of brain tumor screening through magnetic resonance imaging. Here, we will provide a general overview of the screening principles and brain tumor epidemiology, then highlight the major studies examining brain tumor prevalence in asymptomatic populations in order to assess the potential benefits and drawbacks of screening for brain tumors. IMPLICATIONS FOR PRACTICE: Magnetic resonance imaging (MRI) screening in healthy asymptomatic adults can detect both early gliomas and other benign central nervous system abnormalities. Further research is needed to determine whether MRI will improve overall morbidity and mortality for the screened populations and make screening a worthwhile endeavor.

Indexed as

AdultBrain NeoplasmsFemaleHumansMagnetic Resonance ImagingMaleSurvival AnalysisAsymptomaticBrain tumorGlioblastomaMagnetic resonance imagingScreening

Identifiers

PMID30305414
PMCPMC6519753
OpenAlexW2897329785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.