Evidence map›Paper›PMID 30305398›Full record

ArticleThe Journal of biological chemistry2018

Depletion of plasma membrane-associated phosphoinositides mimics inhibition of TRPM7 channels by cytosolic Mg

Tetyana Zhelay, Krystyna B Wieczerzak, Pavani Beesetty, Gerald M Alter, Masayuki Matsushita, J Ashot Kozak

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Transient Receptor Potential (TRP) Channels in Cochlear Function: Looking Beyond Mechanotransduction.Journal of the Association for Research in Otolaryngology : JARO · 2024
    Article
  8. Article
  9. Blockade of TRPV channels by intracellular spermine.The Journal of general physiology · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Effects of Diluent pH on Enrichment and Performance of Dairy Goat X/Y Sperm.Frontiers in cell and developmental biology · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Functional expression of TRPM7 as a CaPhysiological reports · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Tetyana ZhelayFrom the Departments of Neuroscience, Cell Biology, and Physiology and.
Krystyna B WieczerzakFrom the Departments of Neuroscience, Cell Biology, and Physiology and.
Pavani BeesettyFrom the Departments of Neuroscience, Cell Biology, and Physiology and.
Gerald M AlterBiochemistry and Molecular Biology, Wright State University, Dayton, Ohio 45435 and.
Masayuki Matsushitathe Department of Molecular and Cellular Physiology, Graduate School of Medicine, University of the Ryukyus, Okinawa 903-0215, Japan.
J Ashot KozakFrom the Departments of Neuroscience, Cell Biology, and Physiology and. Electronic address: juliusz.kozak@wright.edu.
University of the Ryukyus · JPWright State University · US

Funding

TRPM7 and Cellular pHR01AI114804 · NIAID · WRIGHT STATE UNIVERSITY · PI KOZAK, JULIUSZ ASHOT · 2015 to 2019
$1.8M
Function and regulation of TRPM7 Mg2+-inhibited cation channelsR15AI090613 · NIAID · WRIGHT STATE UNIVERSITY · PI KOZAK, JULIUSZ ASHOT · 2010 to 2010
$251k
NIAID NIH HHS R01 AI114804NIAID NIH HHS R15 AI090613
6 · The paper itself

Abstract

Transient receptor potential cation channel subfamily M member 7 (TRPM7) is an ion channel/protein kinase belonging to the TRP melastatin and eEF2 kinase families. Under physiological conditions, most native TRPM7 channels are inhibited by cytoplasmic Mg

Indexed as

AnimalsBiological TransportCell MembraneCytosolHydrogen-Ion ConcentrationMagnesiumMicePatch-Clamp TechniquesPhosphatidylinositol 4,5-DiphosphatePhosphatidylinositolsPolyaminesProtonsSpermineTRPM Cation ChannelsMagnesiumPhosphatidylinositol 4,5-DiphosphatePhosphatidylinositolsPolyaminesProtonsSpermineTrpm7 protein, mouseTRPM Cation Channelschannel activationgain-of-function mutationmagnesiummutantphosphoinositidepolyaminetransfectiontransient receptor potential channels (TRP channels)TRPMvoltage-sensitive phosphatase

Identifiers

PMID30305398
PMCPMC6254349
OpenAlexW2897798724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.