Evidence map›Paper›PMID 30305357›Full record

ArticleJournal of virology2019

Bone Marrow-Derived CD4

Timothy N Hoang, Justin L Harper, Maria Pino, Hong Wang, Luca Micci, Colin T King, Colleen S McGary, Julia B McBrien, Barbara Cervasi, Guido Silvestri and 1 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. The Hitchhiker Guide to CD4Frontiers in immunology · 2021
    Pooled it
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Timothy N HoangDivision of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, USA.
Justin L HarperDivision of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, USA.
Maria PinoDivision of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, USA.
Hong WangDivision of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, USA.
Luca MicciDivision of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, USA.
Colin T KingDivision of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, USA.
Colleen S McGaryDivision of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, USA.
Julia B McBrienDivision of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, USA.
Barbara CervasiFlow Cytometry Core, Emory Vaccine Center, Emory University, Atlanta, Georgia, USA.
Guido SilvestriDivision of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, USA.
Mirko PaiardiniDivision of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, USA mirko.paiardini@emory.edu.
Emory University · US

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Carlos del Rio · 2002 to 2026
$74.0M
Viral Testing Core-Maintenance of the SPF Breeding Colonies at Yerkes National Primate Research CenterU42OD011023 · OD · EMORY UNIVERSITY · PI Matthew Ryan Gardner · 2018 to 2026
$17.5M
Immune based interventions for HIV eradicationR01AI116379 · NIAID · EMORY UNIVERSITY · PI PAIARDINI, MIRKO · 2015 to 2019
$4.2M
Persistent Virus Reservoirs in SIV-infected MacaquesR33AI104278 · NIAID · EMORY UNIVERSITY · PI PAIARDINI, MIRKO · 2015 to 2017
$1.6M
Targeting Cytolytic Cells to Lymphoid Sites of HIV Persistence.R33AI116171 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI LEDERMAN, MICHAEL MARCEL, PAIARDINI, MIRKO · 2016 to 2018
$1.5M
NIAID NIH HHS P30 AI050409NIAID NIH HHS R01 AI116379NIAID NIH HHS R33 AI104278NIAID NIH HHS R33 AI116171NIH HHS P51 OD011132NIH HHS U42 OD011023
6 · The paper itself

Abstract

The bone marrow (BM) is the key anatomic site for hematopoiesis and plays a significant role in the homeostasis of mature T cells. However, very little is known on the phenotype of BM-derived CD4

Indexed as

AnimalsAnti-Retroviral AgentsBone Marrow CellsCD4-Positive T-LymphocytesCTLA-4 AntigenMacaca mulattaMaleProgrammed Cell Death 1 ReceptorSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusViral LoadVirus ReplicationAnti-Retroviral AgentsCTLA-4 AntigenProgrammed Cell Death 1 Receptorbone marrowcoinhibitory receptorsCTLA-4HIV-1PD-1SIVviral reservoir

Identifiers

PMID30305357
PMCPMC6288341
OpenAlexW2904472947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.