Evidence map›Paper›PMID 30305289›Full record

ArticleDevelopment (Cambridge, England)2018

Leah B Nantie, Randee E Young, Wyatt G Paltzer, Yan Zhang, Randy L Johnson, Jamie M Verheyden, Xin Sun

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Mechanical compression causes lung hypoplasia in congenital diaphragmatic hernia with GATA4 genetic variants.American journal of physiology. Lung cellular and molecular physiology · 2026
    Article
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  9. Review
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  11. Article
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  14. Review
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  16. Review
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Leah B NantieLaboratory of Genetics, Department of Medical Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.
Randee E YoungLaboratory of Genetics, Department of Medical Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.
Wyatt G PaltzerDepartment of Pediatrics, Department of Biological Sciences, University of California-San Diego, La Jolla, CA 92093, USA.
Yan ZhangLaboratory of Genetics, Department of Medical Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.
Randy L JohnsonDepartment of Cancer Biology, University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA.
Jamie M VerheydenDepartment of Pediatrics, Department of Biological Sciences, University of California-San Diego, La Jolla, CA 92093, USA.
Xin SunLaboratory of Genetics, Department of Medical Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA xinsun@ucsd.edu.ORCID 0000-0001-8387-4966
University of Wisconsin–Madison · USThe University of Texas MD Anderson Cancer Center · US

Funding

PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007133 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PERNA, NICOLE T · 1985 to 2023
$16.5M
Wisconsin Allergy Research Training (WISCART) ProgramT32AI007635 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI James E. Gern, DANIEL J JACKSON · 2000 to 2026
$6.5M
Investigating Effects of Viral Infection on Lung DevelopmentR01HL097134 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI LEMANSKE, ROBERT F, SUN, XIN · 2009 to 2013
$2.4M
Genetic Basis of Normal and Pathological Alveologenesis in Lung DevelopmentR01HL142215 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SUN, XIN · 2018 to 2021
$2.0M
Respiratory Deficiencies in Congenital Diaphragmatic HerniaR01HL122406 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI SUN, XIN · 2015 to 2018
$1.8M
Hippo Signaling In Lung Development And Injury RepairF32HL132483 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI NANTIE, LEAH BRENNAN · 2016 to 2017
$70k
NHLBI NIH HHS F32 HL132483NHLBI NIH HHS R01 HL097134NHLBI NIH HHS R01 HL122406NHLBI NIH HHS R01 HL142215NIAID NIH HHS T32 AI007635NIGMS NIH HHS T32 GM007133
6 · The paper itself

Abstract

Lung growth to its optimal size at birth is driven by reiterative airway branching followed by differentiation and expansion of alveolar cell types. How this elaborate growth is coordinated with the constraint of the chest is poorly understood. Here, we investigate the role of Hippo signaling, a cardinal pathway in organ size control, in mouse lung development. Unexpectedly, we found that epithelial loss of the Hippo kinase genes

Indexed as

AirCell DifferentiationRespirationAdaptor Proteins, Signal TransducingAlveolar Epithelial CellsAnimalsBiomarkersBody PatterningCell Cycle ProteinsCell NucleusCell PolarityCell ProliferationEmbryo, MammalianHippo Signaling PathwayMiceMorphogenesisAdaptor Proteins, Signal TransducingBiomarkersCell Cycle ProteinsLats1 protein, mouseLATS2 protein, mousePhosphoproteinsProtein Serine-Threonine KinasesTrans-ActivatorsTumor Suppressor ProteinsWwtr1 protein, mouseYap1 protein, mouseYAP-Signaling ProteinsAlveolarBranchingDevelopmentHippoLungMousePolarity

Identifiers

PMID30305289
PMCPMC6240317
OpenAlexW2896406329

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.