Evidence map›Paper›PMID 30305153›Full record

ArticleTrials2018

Cognitive aids for people with early stage dementia versus treatment as usual (Dementia Early Stage Cognitive Aids New Trial (DESCANT)): study protocol for a randomised controlled trial.

Helen Chester, Paul Clarkson, Linda Davies, Jane Hughes, Muhammad Saiful Islam, Narinder Kapur, Martin Orrell, Julie Peconi, Rosa Pitts, Fiona Poland and 3 more

Abstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Cognitive rehabilitation for people with mild to moderate dementia.The Cochrane database of systematic reviews · 2023
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Helen ChesterPersonal Social Services Research Unit, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK. helen.chester@manchester.ac.uk.ORCID http://orcid.org/0000-0001-6587-6618
Paul ClarksonPersonal Social Services Research Unit, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Linda DaviesManchester Centre for Health Economics, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Jane HughesPersonal Social Services Research Unit, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Muhammad Saiful IslamSwansea Trials Unit, Institute of Life Science 2, Medical School, Swansea University, Swansea, UK.
Narinder KapurResearch Department of Clinical, Educational and Health Psychology, University College London, London, UK.
Martin OrrellInstitute of Mental Health, School of Medicine, University of Nottingham, Nottingham, UK.
Julie PeconiSwansea Trials Unit, Institute of Life Science 2, Medical School, Swansea University, Swansea, UK.
Rosa PittsPersonal Social Services Research Unit, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Fiona PolandSchool of Health Sciences, Faculty of Medicine and Health Sciences, University of East Anglia, Norwich, UK.
Ian RussellSwansea Trials Unit, Institute of Life Science 2, Medical School, Swansea University, Swansea, UK.
David ChallisPersonal Social Services Research Unit, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Members of the HoSt-D (Home Support in Dementia) Programme Management Group

Funding

Department of Health DTC-RP-PG-0311-12003Programme Grants for Applied Research DTC-RP-PG-0311-12003
6 · The paper itself

Abstract

backgroundThere is a growing need for an evidence-based approach to home support for people with dementia and their carers following diagnosis but research on the effectiveness and cost-effectiveness of different approaches is sparse. The Dementia Early Stage Cognitive Aids New Trial (DESCANT) will evaluate the clinical and cost-effectiveness of a range of memory aids, training and support to people with mild to moderate dementia and their carers at home and compares that intervention with treatment as usual. METHODS/

designThis is a multi-site, pragmatic randomised trial preceded by a feasibility study and internal pilot. We aim to allocate at random 360 pairs comprising a person with mild to moderate dementia and an identified carer between the DESCANT intervention and treatment as usual. We assess participants at baseline, 13 and 26 weeks. The primary outcome measure is the Bristol Activities of Daily Living Scale; other participant outcomes include cognition, quality of life, activities of daily living and social networking; carer outcomes include quality of life, sense of competence and mental health. To enhance this quantitative evaluation we are conducting a qualitative component and a process evaluation to assess the implementation process and identify contextual factors associated with variation. DISCUSSION: The DESCANT intervention reflects current policy to enhance the capabilities of people with dementia after diagnosis and their carers. If it is clinically and cost-effective, its modest nature and cost will enhance the likelihood of it being incorporated into mainstream practice.

trial registrationCurrent Controlled Trials, ISRCTN12591717 . Registered on 29 July 2016. Protocol number: 31288: North West - Haydock Research Ethics Committee, 20/06/2016, ref.: 16/NW/0389.

Indexed as

CognitionMemoryActivities of Daily LivingAdaptation, PsychologicalDementiaFeasibility StudiesHumansMulticenter Studies as TopicPilot ProjectsPragmatic Clinical Trials as TopicQuality of LifeTime FactorsTreatment OutcomeUnited KingdomCommunityCost-effectivenessEarly-stage dementiaEffectivenessMemory aidsPragmatic randomised trialProcess evaluationPsychosocial outcomesQuality of life

Identifiers

PMID30305153
PMCPMC6180589

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.