Evidence map›Paper›PMID 30305084›Full record

ArticleLipids in health and disease2018

Cardiovascular risk assessment of dyslipidemic middle-aged adults without overt cardiovascular disease over the period of 2009-2016 in Lithuania.

Sandra Kutkiene, Zaneta Petrulioniene, Aleksandras Laucevicius, Pranas Serpytis, Vytautas Kasiulevicius, Justina Staigyte, Akvile Saulyte, Emilija Petrulionyte, Urte Gargalskaite, Egle Skiauteryte and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lipids in health and disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Sandra KutkieneVilnius University, Faculty of Medicine, Clinic of Cardiac and Vascular Diseases, Vilnius, Lithuania. sandra.kutkiene@santa.lt.
Zaneta PetrulionieneVilnius University, Faculty of Medicine, Clinic of Cardiac and Vascular Diseases, Vilnius, Lithuania.
Aleksandras LauceviciusVilnius University, Faculty of Medicine, Clinic of Cardiac and Vascular Diseases, Vilnius, Lithuania.
Pranas SerpytisVilnius University, Faculty of Medicine, Clinic of Cardiac and Vascular Diseases, Vilnius, Lithuania.
Vytautas KasiuleviciusVilnius University, Faculty of Medicine, Clinic of Internal Diseases, Family Medicine and Oncology, Vilnius, Lithuania.
Justina StaigyteVilnius University, Faculty of Medicine, Vilnius, Lithuania.
Akvile SaulyteVilnius University, Faculty of Medicine, Vilnius, Lithuania.
Emilija PetrulionyteVilnius University, Faculty of Medicine, Vilnius, Lithuania.
Urte GargalskaiteVilnius University, Faculty of Medicine, Vilnius, Lithuania.
Egle SkiauteryteVilnius University, Faculty of Medicine, Vilnius, Lithuania.
Gabija MatuzevicieneVilnius University, Faculty of Medicine, Vilnius, Lithuania.
Milda KovaiteVilnius University Hospital Santaros Klinikos, Santariskiu str. 2, 08661, Vilnius, Lithuania.
Egidija RinkunieneVilnius University, Faculty of Medicine, Clinic of Cardiac and Vascular Diseases, Vilnius, Lithuania.
Vilnius University · LTVilnius University Hospital Santariskiu Klinikos · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular mortality in Lithuania is extremely high and abnormal lipid levels are very common among Lithuanian adults. Dyslipidemia is one of the main independent risk factors for cardiovascular diseases (CVD) leading to high absolute CVD risk. The aim of this study was to assess CVD risk in dyslipidemic middle-aged subjects.

methodsDuring the period of 2009-2016 a total of 92,373 people (58.4% women and 41.6% men) were evaluated. This study included men aged 40-54 and women aged 50-64 without overt CVD.

resultsAny type of dyslipidemia was present in 89.7% of all study population. 7.5% of dyslipidemic patients did not have any other conventional risk factors. Three and more risk factors were detected in 60.1% of dyslipidemic subjects. All analyzed risk factors, except smoking, were more common in dyslipidemic adults compared to subjects without dyslipidemia: arterial hypertension (55.8% vs. 43.3%, p < 0.001), diabetes (11.1% vs. 7.3%, p < 0.001), abdominal obesity (45.3% vs. 30.2%, p < 0.001), BMI ≥30 kg/m

conclusionsAlmost two thirds of dyslipidemic middle-aged Lithuanian adults without overt cardiovascular disease had three or more other CVD risk factors, which synergistically increase absolute risk of CVD. The average 10-year risk of CVD death in patients with dyslipidemia was 1.95%. The importance of managing dyslipidemia as well as other risk factors in order to reduce burden of cardiovascular disease in Lithuania is evident.

Indexed as

AdultCardiovascular DiseasesDiabetes MellitusDyslipidemiasFemaleHumansHypertensionLithuaniaMaleMetabolic SyndromeMiddle AgedRisk AssessmentRisk FactorsSmokingCardiovascular riskClustering of risk factorsDyslipidemiaMiddle-aged populationPrimary preventionSCORE

Identifiers

PMID30305084
PMCPMC6180581
OpenAlexW2808663231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.