ArticleBMC ophthalmology2018
Risk factors of presenile nuclear cataract in health screening study.
Article in BMC ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
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14 citing papers in PubMed, 24 citations in OpenAlex.
- Characteristics of pharyngeal paraesthesia symptoms in patients with obstructive sleep apnoea.Sleep & breathing = Schlaf & Atmung · 2021Trial
- Corneal higher-order aberrations in early-onset cataract patients without identifiable risk factors: a retrospective case-control study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Differential Characteristics, Mechanisms, and Clinical Strategies for Perioperative Dry Eye in Presenile Cataract and Age-Related Cataract.Healthcare (Basel, Switzerland) · 2026Review
- Iron: More than Meets the Eye.Nutrients · 2025Review
- Is Cataract in Patients under 60 Years Associated with Oxidative Stress?Biomedicines · 2023Article
- "Never Judge a Book by its Cover"-The socio-cultural aspects of non-epileptic seizures in India-A case study.Journal of family medicine and primary care · 2023Article
- Increased risk of cataract surgery in patients with allergic disease: a population based cohort study.Scientific reports · 2022Article
- High Incidence of Cataracts in the Follow-Up of Patients Undergoing Percutaneous Coronary Intervention for Chronic Coronary Total Occlusion.Journal of clinical medicine · 2021Article
- Findings from the 45 and Up Study: smoking is not associated with the risk of early-onset cataract.Annals of translational medicine · 2021Article
- Evaluation of Corneal and Lenticular Parameters in Iron Deficiency Anemia.Beyoglu eye journal · 2021Article
- Increased risk of tinnitus in patients with early-onset cataracts: a nationwide population-based case-control study.BMC ophthalmology · 2020Article
- Scanning and transmission electron microscopy study of anterior lens epithelium in presenile cataract.International ophthalmology · 2020Article
- Two Pathogenic Gene Mutations Identified Associating with Congenital Cataract and Iris Coloboma Respectively in a Chinese Family.Journal of ophthalmology · 2020Article
- Correction to: Risk factors of presenile nuclear cataract in health screening study.BMC ophthalmology · 2018Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo identify risk factors for the development of presenile nuclear cataract in health screening test.
methodsThe cross sectional study included a total of 532 eyes of 266 participants aged 30 to 49 years of Samsung Medical Center from February 2013 to April 2015. Presence of nuclear cataract was defined when the log MAR visual acuity with correction was greater than or equal to 0.2 and one or more of the following were met: Pentacam Nuclear Staging (PNS) grading score ≥ 1, average value of nuclear density ≥ 15%, maximum value of nuclear density ≥ 30%. Possible risk factors were obtained from blood tests and questionnaires of a health screening test of Samsung Medical Center. Association between nuclear cataract and risk factors was investigated using univariate and multivariate logistic regression analysis by generalized estimating equation (GEE) models.
resultsFive factors were significantly associated with presenile nuclear cataract: current smoking [odds ratio (OR) = 2.80, 95% confidence interval (CI), 1.10-7.12, p = 0.0310], non-exercise and high amount of daily physical exercise (OR = 3.99, 95% CI, 1.27-12.52, p = 0.0178; OR = 2.92, 95% CI, 1.38-6.22, p = 0.0053), asthma (OR = 8.93, 95% CI, 1.12-71.15, p = 0.0386), tuberculosis (OR = 4.28, 95% CI, 1.36-13.50, p = 0.0131), and higher total iron binding capacity (OR = 1.01, 95% CI, 1.00-1.02, p = 0.0059).
conclusionsPresenile nuclear cataract is related to current smoking, non-exercise or high amount of physical exercise, asthma, tuberculosis, and iron deficiency status. The association of non-exercise group and presenile nuclear cataract seems to be related to co-morbidity. Patients with asthma, tuberculosis, or iron deficiency anemia are recommended to receive frequent ophthalmic examination to detect cataract.
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