ArticleBMC endocrine disorders2018
Vitamin D status in healthy black African adults at a tertiary hospital in Nairobi, Kenya: a cross sectional study.
Article in BMC endocrine disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 14 citations in OpenAlex.
- Serum 25-hydroxyvitamin D levels among women newly diagnosed with breast cancer at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia.BMC women's health · 2026Article
- Article
- Impact of helminth infections during pregnancy on maternal and newborn Vitamin D and on birth outcomes.Scientific reports · 2024Article
- Prevalence of vitamin D deficiency and its association with cardiometabolic risk factors among healthcare workers in the Eastern Cape province, South Africa; cross-sectional study.Scientific reports · 2024Article
- The circadian rhythm of calcium and bone homeostasis in Maasai.American journal of human biology : the official journal of the Human Biology Council · 2022Article
- Prevalence and Predictors of Hypovitaminosis D in Ethiopian HIV-Infected Adults.HIV/AIDS (Auckland, N.Z.) · 2021Article
- Vitamin D3 and K2 and their potential contribution to reducing the COVID-19 mortality rate.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020Article
- Vitamin D Deficiency and Unclear Abdominal Pain in Patients from Low- and Middle-Income Countries.International journal of environmental research and public health · 2019Observational
- Vitamin D levels in patients with recurrent aphthous stomatitis.BMC oral health · 2018Article
- A pilot study to assess Vitamin D and serum ferritin levels among prospective female blood donors with low hemoglobin levels.Asian journal of transfusion scienceArticle
- Association of Atherogenic Combined Index, hs-CRP/HDL-C Ratio, and TC/HDL-C-BMI Index with Low Vitamin D Levels among PLWH on Antiretroviral Therapy: A Cross-Sectional Study in Southwestern Uganda.Journal of the International Association of Providers of AIDS CareArticle
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4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundVitamin D has been known since the twentieth Century for its benefits in bone health. Recent observational studies have demonstrated its benefits in infectious diseases such as tuberculosis and non-communicable diseases such as diabetes mellitus, cardiovascular diseases and cancer. This has led to a dramatic increase in testing among adults. The cut-offs for vitamin D deficiency have been debated for decades and the current cut off is derived from a Caucasian population. Studies done among black African adults in Africa are few with vitamin D deficiency ranging from 5 to 91%. A few cut- offs have correlated vitamin D deficiency to physiological markers such as parathyroid hormone (PTH), calcium and phosphate with varying results.
methodsThis was a cross sectional study carried out among blood donors at Aga Khan University hospital, Nairobi (AKUHN) from March to May 2015. Vitamin D (25(OH)D) levels were assayed and correlated with PTH, calcium and phosphate.
resultsA total of 253 individuals were included in the final analysis. The proportion of study participants who had a 25(OH) D level of < 20 ng/ml thus classified as vitamin D deficient was 17.4% (95% C.I 12.73-22.07). The 25(OH) D level that coincided with a significant increase in PTH was 30 ng/ml. Males were less likely to be vitamin D deficient (O.R 0.48 (C.I 0.233-0.993) p 0.04). Sunshine exposure for ≥3 h per day reduced the odds of being Vitamin D deficient though this was not statistically significant after multivariate regression analysis.
conclusionsWe found a much lower prevalence of Vitamin D deficiency compared to many similar studies carried out in sub-Saharan Africa possibly due to the recruitment of healthy individuals and the proximity of Nairobi to the equator which allows for considerable exposure to sunshine. Vitamin D levels below 30 ng/mL was associated with a significant rise in PTH levels, suggesting that this cut off could be appropriate for defining Vitamin D deficiency in the population served by our laboratory.
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