ArticleBMC plant biology2018
Non-target site-based resistance to tribenuron-methyl and essential involved genes in Myosoton aquaticum (L.).
Article in BMC plant biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 56 citations in OpenAlex.
- High Temperatures Are Required for Expression of Metabolic Resistance to Cyhalofop-Butyl in a Biotype ofJournal of agricultural and food chemistry · 2026Article
- iTRAQ-based quantitative proteomic analysis of herbicide stress in Avena ludoviciana Durieu.Scientific reports · 2025Article
- 2,2',4,4'-Tetrabromodiphenyl Ether (BDE-47) at Environmental Levels Influenced Photosynthesis in the Mangrove SpeciesToxics · 2024Article
- Metabolism-Based Herbicide Resistance to Mesosulfuron-methyl and Identification of Candidate Genes inPlants (Basel, Switzerland) · 2024Article
- Weed biology and management in the multi-omics era: Progress and perspectives.Plant communications · 2024Review
- Target-site mutations Ile1781Leu and Ile2041Asn in thePlant direct · 2024Article
- A high diversity of non-target site resistance mechanisms to acetolactate-synthase (ALS) inhibiting herbicides has evolved within and among field populations of common ragweed (Ambrosia artemisiifolia L.).BMC plant biology · 2023Article
- Effect of Brassinolide on Soil Microorganisms in Millet Field Polluted by Tribenuron-Methyl.Microorganisms · 2023Article
- Article
- Comprehensive insights into herbicide resistance mechanisms in weeds: a synergistic integration of transcriptomic and metabolomic analyses.Frontiers in plant science · 2023Review
- Cytochrome P450International journal of molecular sciences · 2022Article
- Cytochrome P450 CYP709C56 metabolizing mesosulfuron-methyl confers herbicide resistance in Alopecurus aequalis.Cellular and molecular life sciences : CMLS · 2022Article
- An Asp376Glu substitution inFrontiers in plant science · 2022Article
- The analysis of reference genes expression stability in susceptible and resistant Apera spica-venti populations under herbicide treatment.Scientific reports · 2021Article
- The Basis of Tolerance Mechanism to Metsulfuron-Methyl inPlants (Basel, Switzerland) · 2021Article
- Transcriptome analysis reveals gene responses to herbicide, tribenuron methyl, in Brassica napus L. during seed germination.BMC genomics · 2021Article
- Non-target Site Herbicide Resistance Is Conferred by Two Distinct Mechanisms in Black-Grass (Frontiers in plant science · 2021Article
- Non-Target-Site Resistance to Herbicides: Recent Developments.Plants (Basel, Switzerland) · 2019Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundWater chickweed (Myosoton aquaticum (L.)) is a dicot broadleaf weed that is widespread in winter fields in China, and has evolved serious resistance to acetolactate synthase (ALS) inhibiting herbicides.
resultsWe identified a M. aquaticum population exhibiting moderate (6.15-fold) resistance to tribenuron-methyl (TM). Target-site ALS gene sequencing revealed no known resistance mutations in these plants, and the in vitro ALS activity assays showed no differences in enzyme sensitivity between susceptible and resistant populations; however, resistance was reversed by pretreatment with the cytochrome P450 (CYP) monooxygenase inhibitor malathion. An RNA sequencing transcriptome analysis was performed to identify candidate genes involved in metabolic resistance, and the unigenes obtained by de novo transcriptome assembly were annotated across seven databases. In total, 34 differentially expressed genes selected by digital gene expression analysis were validated by quantitative real-time (qRT)-PCR. Ten consistently overexpressed contigs, including four for CYP, four for ATP-binding cassette (ABC) transporter, and two for peroxidase were further validated by qRT-PCR using additional plants from resistant and susceptible populations. Three CYP genes (with homology to CYP734A1, CYP76C1, and CYP86B1) and one ABC transporter gene (with homology to ABCC10) were highly expressed in all resistant plants.
conclusionThe mechanism of TM resistance in M. aquaticum is controlled by NTSR rather than TSR. Four genes, CYP734A1, CYP76C1, CYP86B1, and ABCC10 could play essential role in metabolic resistance to TM and justify further functional studies. To our knowledge, this is the first large-scale transcriptome analysis of genes associated with NTSR in M. aquaticum using the Illumina platform. Our data provide resource for M. aquaticum biology, and will facilitate the study of herbicide resistance mechanism at the molecular level in this species as well as in other weeds.
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