ArticleKorean journal of pediatrics2018
Evaluation of prolonged pain in preterm infants with pneumothorax using heart rate variability analysis and EDIN (Échelle Douleur Inconfort Nouveau-Né, neonatal pain and discomfort scale) scores.
Article in Korean journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Clinical rating scales for assessing pain in newborn infants.The Cochrane database of systematic reviews · 2025Pooled it
- Efficacy of intravenous immunoglobulin following plasma exchange in the management of ABO haemolytic disease of the newborn.Vox sanguinis · 2026Trial
- Validation and reliability of a scale for prolonged pain assessment in Brazilian neonates.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- The First 13 Years of "Percorso Giacomo": Patients' Outcomes.Children (Basel, Switzerland) · 2026Article
- Pain assessment and determination methods with wearable sensors: a scoping review.Medical & biological engineering & computing · 2026Article
- Physiological correlates of pain in preterm infants: evidence from a meta-analytic approach.Frontiers in pediatrics · 2026Review
- Baseline NIPEEuropean journal of pediatrics · 2025Observational
- The EVENDOL Pain Scale Validation for Acute Non-Procedural Neonatal Pain in Term Neonates: Reliability and Validity in Maternity Wards.Paediatric & neonatal pain · 2025Article
- The Newborn Infant Parasympathetic Evaluation Index for Assessment of Procedural Pain and Discomfort in Mechanically Ventilated Pediatric Intensive Care Patients: A Prospective, Exploratory, Observational Study.Paediatric anaesthesia · 2025Observational
- Pain and heart rate variability in neonates receiving dexmedetomidine.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Biomarkers for assessing pain and pain relief in the neonatal intensive care unit.Frontiers in pain research (Lausanne, Switzerland) · 2024Review
- Methods for analyzing infant heart rate variability: A preliminary study.Birth defects research · 2023Article
- Usefulness of two types of pain monitors in newborns treated in NICU, in the opinion of experts: Results of the survey.Journal of mother and child · 2022Article
- Neonatal heart rate variability: a contemporary scoping review of analysis methods and clinical applications.BMJ open · 2021Article
- The newborn infant parasympathetic evaluation in pediatric and neonatology: a literature review.Journal of clinical monitoring and computing · 2021Review
- Procedural Pain Assessment in Infants Without Analgosedation: Comparison of Newborn Infant Parasympathetic Evaluation and Skin Conductance Activity - A Pilot Study.Frontiers in pediatrics · 2021Article
- Newborn infant parasympathetic evaluation for the assessment of analgosedation adequacy in infants treated by mechanical ventilation - a multicenter pilot study.Archives of medical science : AMS · 2021Article
- Heart Rate Variability in the Perinatal Period: A Critical and Conceptual Review.Frontiers in neuroscience · 2020Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe EDIN scale (Échelle Douleur Inconfort Nouveau-Né, neonatal pain and discomfort scale) and heart rate variability has been used for the evaluation of prolonged pain. The aim of our study was to assess the value of the newborn infant parasympathetic evaluation (NIPE) index and EDIN scale for the evaluation of prolonged pain in preterm infants with chest tube placement due to pneumothorax.
methodsThis prospective observational study assessed prolonged pain in preterm infants with a gestational age between 33 and 35 weeks undergoing installation of chest tubes. Prolonged pain was assessed using the EDIN scale and NIPE index.
resultsThere was a significant correlation between the EDIN scale and NIPE index (r=-0.590, P=0.003). Prolonged pain is significantly more severe in the first 6 hours following chest tube installation (NIPE index: 60 [50-86] vs. 68 [45-89], P<0.002; EDIN score: 8 [7-11] vs. 6 [4-8], P<0.001).
conclusionProlonged pain can be accurately assessed with the EDIN scale and NIPE index. However, evaluation with the EDIN scale is time-consuming. The NIPE index can provide instantaneous assessment of prolonged and continuous pain.
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