Evidence map›Paper›PMID 30304862›Full record

ArticleMolecules (Basel, Switzerland)2018

High Potency of

Alessandra Oliva, Silvia Costantini, Massimiliano De Angelis, Stefania Garzoli, Mijat Božović, Maria Teresa Mascellino, Vincenzo Vullo, Rino Ragno

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Article
  2. Review
  3. Efficacy ofMicroorganisms · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Antimicrobial activity of cinnamaldehyde against multidrug-resistant Klebsiella pneumoniae: an in vitro and in vivo study.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  9. Review
  10. Synergistic Inhibition of Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Comparison of the Anti-bacterial Efficacy ofFrontiers in oral health · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alessandra OlivaDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy. alessandra.oliva@uniroma1.it.
Silvia CostantiniDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy. silviacostantini89@gmail.com.
Massimiliano De AngelisDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy. massimiliano.deangelis@uniroma1.it.
Stefania GarzoliRome Center for Molecular Design, Department of Drug Chemistry and Technology, Sapienza University, P.le Aldo Moro 5, 00185 Rome, Italy. stefania.garzoli@uniroma1.it.ORCID 0000-0001-8535-0533
Mijat BožovićFaculty of Natural Sciences and Mathematics, University of Montenegro, Džordža Vašingtona bb, 81000 Podgorica, Montenegro. mijatboz@gmail.com.ORCID 0000-0001-6718-8800
Maria Teresa MascellinoDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy. mariateresa.mascellino@uniroma1.it.
Vincenzo VulloDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy. vincenzo.vullo@uniroma1.it.
Rino RagnoRome Center for Molecular Design, Department of Drug Chemistry and Technology, Sapienza University, P.le Aldo Moro 5, 00185 Rome, Italy. rino.ragno@uniroma1.it.ORCID 0000-0001-5399-975X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHerein, an extended investigation of Tea tree oil (TTO) against a number of multi-drug resistant (MDR) microorganisms in liquid and vapor phases is reported.

methodsThe activity of TTO was tested against methicillin-sensitive

resultsTTO showed a potent bactericidal activity against all the tested microorganisms. TTO in combination with each reference antimicrobial showed a high level of synergism at sub-inhibitory concentrations, particularly with oxacillin (OXA) against MRSA. The VP assay showed high activity of TTO against CR-Ab.

conclusionEvaluation of in-vitro activity clearly indicated TTO as a potential effective antimicrobial treatment either alone or in association with known drugs against MDR. Therefore, TTO could represent the basis for a possible role in non-conventional regimens against

Indexed as

Drug Resistance, Multiple, BacterialAnti-Bacterial AgentsDrug SynergismGas Chromatography-Mass SpectrometryGram-Negative BacteriaMelaleucaMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsOils, VolatilePhytochemicalsTea Tree OilAnti-Bacterial AgentsOils, VolatilePhytochemicalsTea Tree Oilcarbapenem-resistant microorganismsessential oilsMelaleuca alternifoliamethicillin-resistant Staphylococcus aureusmulti-drug resistant bacteria

Identifiers

PMID30304862
PMCPMC6222846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.