Evidence map›Paper›PMID 30304826›Full record

ArticleInternational journal of molecular sciences2018

Comprehensive Analysis of MicroRNA⁻Messenger RNA from White Yak Testis Reveals the Differentially Expressed Molecules Involved in Development and Reproduction.

Quanwei Zhang, Qi Wang, Yong Zhang, Shuru Cheng, Junjie Hu, Youji Ma, Xingxu Zhao

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Exploring the Mechanism of HInternational journal of molecular sciences · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. MiRNAs Expression Profiling of Bovine (International journal of molecular sciences · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Quanwei ZhangCollege of Veterinary Medicine, Gansu Agriculture University, Lanzhou 730070, China. zhangqw@gsau.edu.cn.ORCID 0000-0002-5476-508X
Qi WangCollege of Veterinary Medicine, Gansu Agriculture University, Lanzhou 730070, China. forever45214125@126.com.
Yong ZhangCollege of Veterinary Medicine, Gansu Agriculture University, Lanzhou 730070, China. zhychy@163.com.
Shuru ChengCollege of Animal Science and Technology, Gansu Agriculture University, Lanzhou 730070, China. chengsr@gsau.edu.cn.
Junjie HuCollege of Veterinary Medicine, Gansu Agriculture University, Lanzhou 730070, China. Hujj@gsau.edu.cn.
Youji MaCollege of Animal Science and Technology, Gansu Agriculture University, Lanzhou 730070, China. mayj@gsau.edu.cn.
Xingxu ZhaoCollege of Veterinary Medicine, Gansu Agriculture University, Lanzhou 730070, China. zhaoxx@gsau.edu.cn.

Funding

Chinese National 863 Plan Project Project No. 2013AA102505-3Gansu Natural Science Foundation 1610RJZA097Natural Science Foundation of Chin No. 31760753
6 · The paper itself

Abstract

Testis development is a vital and tightly regulated process in mammals. Understanding the biological mechanisms underlying testis development will benefit the animal reproduction industry. Expression changes in microRNA and messenger RNA in response to dynamic regulation effects have been associated with this process. However, very little is known about the roles of these molecules in yak development. Using whole-genome small RNA and messenger RNA sequencing, we performed a comprehensive analysis of the microRNA⁻messenger RNA interaction network expression in the testicles of Tianzhu white yaks during three developmental stages. Using Short Time-series Expression Miner analysis we identified 589 differentially expressed microRNAs (DERs) and 3383 differentially expressed messenger RNAs (DEGs) in the three age groups. A total of 93 unique DEGs are primarily involved in reproduction and testis development. Subsequently, four integration networks were constructed according to the DEGs and DERs in three biological processes. Nineteen DEGs were potentially regulated by 60 DERs, of which miR-574 and target gene

Indexed as

Gene Expression RegulationAnimalsCattleComputational BiologyGene OntologyGene Regulatory NetworksHigh-Throughput Nucleotide SequencingMaleMicroRNAsReproducibility of ResultsReproductionRNA InterferenceRNA, MessengerSpermatogenesisTestisTranscriptomeMicroRNAsRNA, MessengerdevelopmentmicroRNA–messenger RNAreproductionspermatogenesisyak

Identifiers

PMID30304826
PMCPMC6213350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.