Evidence map›Paper›PMID 30304782›Full record

ArticleMolecules (Basel, Switzerland)2018

2'-

Thananjeyan Balasubramaniyam, Takumi Ishizuka, Chao-Da Xiao, Hong-Liang Bao, Yan Xu

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Z-form DNA-RNA hybrid blocks DNA replication.Nucleic acids research · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Structure and Formation of Z-DNA and Z-RNA.Molecules (Basel, Switzerland) · 2023
    Review
  12. Article
  13. Viral Z-RNA triggers ZBP1-dependent cell death.Current opinion in virology · 2021
    Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thananjeyan BalasubramaniyamDivision of Chemistry, Department of Medical Sciences, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan. balasubramaniyam_thananjeyan@med.miyazaki-u.ac.jp.
Takumi IshizukaDivision of Chemistry, Department of Medical Sciences, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan. tishizuka@med.miyazaki-u.ac.jp.ORCID 0000-0003-0956-784X
Chao-Da XiaoDivision of Chemistry, Department of Medical Sciences, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan. choutatsu_shou@med.miyazaki-u.ac.jp.
Hong-Liang BaoDivision of Chemistry, Department of Medical Sciences, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan. xiaobujiao@163.com.
Yan XuDivision of Chemistry, Department of Medical Sciences, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan. xuyan@med.miyazaki-u.ac.jp.ORCID 0000-0003-0379-8866

Funding

Japan Society for the Promotion of Science 17H03091
6 · The paper itself

Abstract

In contrast to Z-DNA that was stabilized and well-studied for its structure by chemical approaches, the stabilization and structural study of Z-RNA remains a challenge. In this study, we developed a Z-form RNA stabilizer m⁸Gm, and demonstrated that incorporation of m⁸Gm into RNA can markedly stabilize the Z-RNA at low salt conditions. Using the m⁸Gm-contained Z-RNA, we determined the structure of Z-RNA and investigated the interaction of protein and Z-RNA.

Indexed as

Circular DichroismGuanosineMagnetic Resonance SpectroscopyModels, MolecularNucleic Acid ConformationRNAStructure-Activity RelationshipThermodynamics8-methylguanosineGuanosineRNAcircular dichroismNMRsynthesis of oligonucleotideZ-RNA structure

Identifiers

PMID30304782
PMCPMC6222775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.