Evidence map›Paper›PMID 30304644›Full record

Trial reportEuropean journal of preventive cardiology2019

The effects and costs of home-based rehabilitation for heart failure with reduced ejection fraction: The REACH-HF multicentre randomized controlled trial.

Hasnain M Dalal, Rod S Taylor, Kate Jolly, Russell C Davis, Patrick Doherty, Jackie Miles, Robin van Lingen, Fiona C Warren, Colin Green, Jennifer Wingham and 12 more

Erratum issuedOpen access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European journal of preventive cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 77 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 15 pooled it
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 15 syntheses or guidelines pooled it, 164 citations in OpenAlex.

  1. Pooled it
  2. Exercise-based cardiac rehabilitation for adults with heart failure.The Cochrane database of systematic reviews · 2024
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  4. Benefits of Using Smartphones and Other Digital Methods in Achieving Better Cardiac Rehabilitation Goals: A Systematic Review and Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2023
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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 12 institutions in 1 country.

Hasnain M Dalal1 Institute of Health Research, University of Exeter Medical School, Exeter, UK.
Rod S Taylor1 Institute of Health Research, University of Exeter Medical School, Exeter, UK.
Kate Jolly3 Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
Russell C Davis4 Cardiology Department, Sandwell & West Birmingham Hospitals NHS Trust, Birmingham, UK.
Patrick Doherty5 Department of Health Sciences, University of York, York, UK.
Jackie Miles6 Research and Development, Aneurin Bevan University Health Board, St Woolos Hospital, Newport, UK.
Robin van Lingen7 Duchy Hospital, Truro, UK.
Fiona C Warren1 Institute of Health Research, University of Exeter Medical School, Exeter, UK.
Colin Green1 Institute of Health Research, University of Exeter Medical School, Exeter, UK.
Jennifer Wingham1 Institute of Health Research, University of Exeter Medical School, Exeter, UK.
Colin Greaves8 Institute of Health Research, University of Exeter Medical School, Exeter, UK.
Susannah Sadler1 Institute of Health Research, University of Exeter Medical School, Exeter, UK.
Melvyn Hillsdon9 Sport and Health Sciences, University of Exeter, Exeter, UK.
Charles Abraham10 Institute of Health Research, University of Exeter Medical School, Exeter, UK.
Nicky Britten1 Institute of Health Research, University of Exeter Medical School, Exeter, UK.
Julia Frost1 Institute of Health Research, University of Exeter Medical School, Exeter, UK.
Sally Singh11 Centre for Exercise and Rehabilitation Science, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, UK.
Christopher Hayward12 Peninsula Clinical Trials Unit, University of Plymouth, Plymouth, UK.
Victoria Eyre13 Re:Cognition Health, London, UK.
Kevin Paul14 REACH-HF Patient and Public Involvement Group, c/o Research, Development & Innovation, Royal Cornwall Hospitals NHS Trust, Truro, UK.
Chim C Lang15 School of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.
Karen Smith16 School of Nursing and Health Sciences, University of Dundee, Dundee, UK.
University of Exeter · GBUniversity of Dundee · GBCambridge Cognition (United Kingdom) · GBDuchy Hospital · GBGlenfield Hospital · GBRoyal Cornwall Hospital · GBRoyal Cornwall Hospital Trust · GBSandwell & West Birmingham Hospitals NHS Trust · GBSt Woolos Hospital · GBUniversity of Birmingham · GBUniversity of Plymouth · GBUniversity of York · GB

Funding

Department of Health RP-PG-1210-12004
6 · The paper itself

Abstract

backgroundCardiac rehabilitation improves health-related quality of life (HRQoL) and reduces hospitalizations in patients with heart failure, but international uptake of cardiac rehabilitation for heart failure remains low. DESIGN AND

methodsThe aim of this multicentre randomized trial was to compare the REACH-HF (Rehabilitation EnAblement in CHronicHeart Failure) intervention, a facilitated self-care and home-based cardiac rehabilitation programme to usual care for adults with heart failure with reduced ejection fraction (HFrEF). The study primary hypothesis was that the addition of the REACH-HF intervention to usual care would improve disease-specific HRQoL (Minnesota Living with Heart Failure questionnaire (MLHFQ)) at 12 months compared with usual care alone.

resultsThe study recruited 216 participants, predominantly men (78%), with an average age of 70 years and mean left ventricular ejection fraction of 34%. Overall, 185 (86%) participants provided data for the primary outcome. At 12 months, there was a significant and clinically meaningful between-group difference in the MLHFQ score of -5.7 points (95% confidence interval -10.6 to -0.7) in favour of the REACH-HF intervention group ( p = 0.025). With the exception of patient self-care ( p < 0.001) there was no significant difference in other secondary outcomes, including clinical events ( p > 0.05) at follow-up compared with usual care. The mean cost of the REACH-HF intervention was £418 per participant.

conclusionsThe novel REACH-HF home-based facilitated intervention for HFrEF was clinically superior in disease-specific HRQoL at 12 months and offers an affordable alternative to traditional centre-based programmes to address current low cardiac rehabilitation uptake rates for heart failure.

Indexed as

Cardiac RehabilitationHome Care ServicesSelf CareStroke VolumeVentricular Function, LeftAgedAged, 80 and overCost-Benefit AnalysisFemaleHealth Care CostsHeart FailureHumansMaleMiddle AgedQuality of LifeRecovery of FunctionCardiac rehabilitationhealth-related quality of lifeheart failurehome-basedrandomized controlled trialself-management

Identifiers

PMID30304644
PMCPMC6376602
OpenAlexW2898002757

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.