ArticleRevista Brasileira de terapia intensiva
Risk factors for extubation failure in the intensive care unit.
Article in Revista Brasileira de terapia intensiva. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- [ Extubation failure predictors in the release process of invasive mechanical ventilatory support in pediatrics]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2025Article
- Overnight extubation and risk of extubation failure in patients in the pediatric intensive care unit: an exploratory review.Frontiers in pediatrics · 2025Review
- Impact of extubation failure on the duration of mechanical ventilation in the pediatric population.Einstein (Sao Paulo, Brazil) · 2025Observational
- Machine learning-based risk prediction model construction of difficult weaning in ICU patients with mechanical ventilation.Scientific reports · 2024Article
- Using machine-learning models to predict extubation failure in neonates with bronchopulmonary dysplasia.BMC pulmonary medicine · 2024Article
- Predictors and outcomes of extubation failures in a pediatric intensive care unit: A retrospective study.Journal of Taibah University Medical Sciences · 2024Article
- Successful Recovery of a Catatonic Patient with Severe Pneumonia and Respiratory Failure: Modified Electroconvulsive Therapy Following Tracheotomy.Actas espanolas de psiquiatria · 2024Article
- Left atrial strain in neonates with congenital diaphragmatic hernia and length of stay in pediatric intensive care unit.Frontiers in pediatrics · 2024Article
- Development of a clinical prediction tool for extubation failure in pediatric cardiac intensive care unit.Frontiers in pediatrics · 2024Article
- Defining predictors for successful mechanical ventilation weaning, using a data-mining process and artificial intelligence.Scientific reports · 2023Article
- Association Between Dead Space to Tidal Volume Ratio and Duration of Respiratory Support After Extubation in Critically Ill Children.Respiratory care · 2023Article
- Prevalence, Risk Factors, and Outcomes of Airway Versus Non-Airway Pediatric Extubation Failure.Respiratory care · 2023Article
- Tests and Indices Predicting Extubation Failure in Children: A Systematic Review and Meta-analysis.Pulmonary therapy · 2023Review
- Predictive factors of extubation failure in pediatric cardiac intensive care unit: A single-center retrospective study from Thailand.Frontiers in pediatrics · 2023Article
- Pediatric Ventilation Liberation: A Survey of International Practice Among 555 Pediatric Intensivists.Critical care explorations · 2022Article
- Accuracy and Sensitivity of Clinical Parameters in Predicting Successful Extubation in Patients with Acute Brain Injury.Neurology international · 2022Article
- Impairment in Preextubation Alveolar Gas Exchange Is Associated With Postextubation Respiratory Support Needs in Infants After Cardiac Surgery.Critical care explorations · 2022Article
- Ventilation Weaning and Extubation Readiness in Children in Pediatric Intensive Care Unit: A Review.Frontiers in pediatrics · 2022Review
- Characteristics and Risk Factors of Children Requiring Prolonged Mechanical Ventilation vs. Non-prolonged Mechanical Ventilation in the PICU: A Prospective Single-Center Study.Frontiers in pediatrics · 2022Article
- Development and Validation of a Machine-Learning Model for Prediction of Extubation Failure in Intensive Care Units.Frontiers in medicine · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the risk factors for extubation failure in the intensive care unit.
methodsThe present case-control study was conducted in an intensive care unit. Failed extubations were used as cases, while successful extubations were used as controls. Extubation failure was defined as reintubation being required within the first 48 hours of extubation.
resultsOut of a total of 956 patients who were admitted to the intensive care unit, 826 were subjected to mechanical ventilation (86%). There were 30 failed extubations and 120 successful extubations. The proportion of failed extubations was 5.32%. The risk factors found for failed extubations were a prolonged length of mechanical ventilation of greater than 7 days (OR = 3.84, 95%CI = 1.01 - 14.56, p = 0.04), time in the intensive care unit (OR = 1.04, 95%CI = 1.00 - 1.09, p = 0.03) and the use of sedatives for longer than 5 days (OR = 4.81, 95%CI = 1.28 - 18.02; p = 0.02).
conclusionPediatric patients on mechanical ventilation were at greater risk of failed extubation if they spent more time in the intensive care unit and if they were subjected to prolonged mechanical ventilation (longer than 7 days) or greater amounts of sedative use.
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