ArticlePLoS genetics2018
Rice transcription factor OsMADS25 modulates root growth and confers salinity tolerance via the ABA-mediated regulatory pathway and ROS scavenging.
Article in PLoS genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 1 of them a synthesis that pooled it.
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Who cites it
85 citing papers in PubMed, 1 synthesis or guideline pooled it, 268 citations in OpenAlex.
- Meta-analysis of identified genomic regions and candidate genes underlying salinity tolerance in rice (Oryza sativa L.).Scientific reports · 2024Pooled it
- Integrative transcriptional regulatory networks governing cereal root responses to heavy metals and drought.Plant cell reports · 2026Review
- Roles of MADS-box transcription factors in plant responses to abiotic and biotic stresses.Plant communications · 2026Review
- Linking Superoxide Production and Scavenging in Plant Development.Plant, cell & environment · 2026Review
- Knockout of the OsNAC113 Transcription Factor Causes High Salt Resistance in Rice.Plants (Basel, Switzerland) · 2025Article
- OsGSTT3 regulates seed germination by modulating reactive oxygen species homeostasis in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Utilization of MADS-Box genes for agricultural advancement: current insights and future prospects.Molecular biology reports · 2025Review
- Genome-wide association study uncovers a novel gene responsible for rice seedling submergence tolerance.Plant biotechnology journal · 2025Article
- Recent advances in improving yield and immunity through transcription factor engineering.Journal of integrative plant biology · 2025Review
- Rice Peroxygenase-9 Negatively Regulates Production of Reactive Oxygen Species and Increases Cellular Resistance to Abiotic Stress.International journal of molecular sciences · 2025Article
- Overexpression of the ABA Synthesis Gene OsABA2 Enhances Seed Storability in Rice.Rice (New York, N.Y.) · 2025Article
- Genome-wide identification, characterization, and expression analysis of the MADS-box gene family in grass pea (Lathyrus sativus) under salt stress conditions.BMC genomics · 2025Article
- Oxidative Stress in Rice (Plants (Basel, Switzerland) · 2025Review
- Interplay between auxin and abiotic stresses in maize.Journal of experimental botany · 2025Review
- Molecular Alchemy: Converting Stress into Resilience via Secondary Metabolites and Calcium Signaling in Rice.Rice (New York, N.Y.) · 2025Review
- The involvement of auxin response factor OsARF7 in positively regulating root development by mediating the expression of OsCRL1 in rice (Oryza sativa L.).Plant molecular biology · 2025Article
- Natural variation in OsMADS1 transcript splicing affects rice grain thickness and quality by influencing monosaccharide loading to the endosperm.Plant communications · 2025Article
- Dual application of β-sitosterol and biochar reduces copper toxicity in bamboo via improved redox homeostasis.Frontiers in plant science · 2025Article
- Multiscale responses to combined drought and salinity stress inFrontiers in plant science · 2025Review
- MIKC-type MADS-box transcription factor OsMADS31 positively regulates salinity tolerance in rice.Frontiers in plant science · 2025Article
25 more citing papers are in PubMed but not listed here.
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8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant roots are constantly exposed to a variety of abiotic stresses, and high salinity is one of the major limiting conditions that impose constraints on plant growth. In this study, we describe that OsMADS25 is required for the root growth as well as salinity tolerance, via maintaining ROS homeostasis in rice (Oryza sativa). Overexpression of OsMADS25 remarkably enhanced the primary root (PR) length and lateral root (LR) density, whereas RNAi silence of this gene reduced PR elongation significantly, with altered ROS accumulation in the root tip. Transcriptional activation assays indicated that OsMADS25 activates OsGST4 (glutathione S-transferase) expression directly by binding to its promoter. Meanwhile, osgst4 mutant exhibited repressed growth and high sensitivity to salinity and oxidative stress, and recombinant OsGST4 protein was found to have ROS-scavenging activity in vitro. Expectedly, overexpression of OsMADS25 significantly enhanced the tolerance to salinity and oxidative stress in rice plants, with the elevated activity of antioxidant enzymes, increased accumulation of osmoprotective solute proline and reduced frequency of open stoma. Furthermore, OsMADS25 specifically activated the transcription of OsP5CR, a key component of proline biosynthesis, by binding to its promoter. Interestingly, overexpression of OsMADS25 raised the root sensitivity to exogenous ABA, and the expression of ABA-dependent stress-responsive genes was elevated greatly in overexpression plants under salinity stress. In addition, OsMADS25 seemed to promote auxin signaling by activating OsYUC4 transcription. Taken together, our findings reveal that OsMADS25 might be an important transcriptional regulator that regulates the root growth and confers salinity tolerance in rice via the ABA-mediated regulatory pathway and ROS scavenging.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.